ID I3KNG2_ORENI Unreviewed; 281 AA.
AC I3KNG2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Polyhomeotic-like protein 2 {ECO:0000313|Ensembl:ENSONIP00000022657.1};
GN Name=LOC100708466 {ECO:0000313|Ensembl:ENSONIP00000022657.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000022657.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000022657.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_003454324.1; XM_003454276.4.
DR RefSeq; XP_005458859.1; XM_005458802.3.
DR AlphaFoldDB; I3KNG2; -.
DR STRING; 8128.ENSONIP00000022657; -.
DR Ensembl; ENSONIT00000022677.2; ENSONIP00000022657.1; ENSONIG00000017983.2.
DR GeneID; 100708466; -.
DR KEGG; onl:100708466; -.
DR CTD; 171465; -.
DR eggNOG; ENOG502QS5Q; Eukaryota.
DR GeneTree; ENSGT00940000154964; -.
DR HOGENOM; CLU_047131_0_0_1; -.
DR InParanoid; I3KNG2; -.
DR OMA; MGAMNIK; -.
DR OrthoDB; 5399754at2759; -.
DR TreeFam; TF331299; -.
DR Proteomes; UP000005207; Linkage group LG20.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF86; POLYHOMEOTIC-LIKE PROTEIN 2; 1.
DR Pfam; PF16616; PHC2_SAM_assoc; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 75..109
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT DOMAIN 217..281
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
SQ SEQUENCE 281 AA; 31280 MW; C12123192CBFDB2D CRC64;
MTSGNGNTNS TQHNGESKRA QAIVKSHILT HLIEGFVIQE GAEPFPVERP SFSIENLRRY
TPDSKMDSLS AKEVKGQQEP MLTCELCGRV DFAYIFKRSK RFCSTVCAKR YNVGCTKRMG
LFPNRKTTLE NMKKQKTVNG NHKNTIIESK KKTAPCVQKP AAHSVHPAQG DSNHCSDLSV
YKRPPSPVSA SQRLPVTQGS ELPLLHHGFL PSDPGQWNIE NVYKFISSLP GCLEIAEEFR
SQEIDGQALL LLKEDHLMGT MNIKLGPALK IFAQISMLKD S
//
