ID I3KPT2_ORENI Unreviewed; 865 AA.
AC I3KPT2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Zinc finger, ZZ-type containing 3 {ECO:0000313|Ensembl:ENSONIP00000023127.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000023127.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000023127.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3KPT2; -.
DR STRING; 8128.ENSONIP00000045891; -.
DR Ensembl; ENSONIT00000023147.2; ENSONIP00000023127.2; ENSONIG00000018369.2.
DR eggNOG; ENOG502QS4F; Eukaryota.
DR GeneTree; ENSGT00390000005307; -.
DR HOGENOM; CLU_319257_0_0_1; -.
DR TreeFam; TF106396; -.
DR Proteomes; UP000005207; Linkage group LG18.
DR GO; GO:0070461; C:SAGA-type complex; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR InterPro; IPR037830; ZZZ3.
DR PANTHER; PTHR22705; ZINC FINGER, ZZ DOMAIN CONTAINING 3; 1.
DR PANTHER; PTHR22705:SF0; ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 610..670
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 610..666
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 780..839
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 1..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 566..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..451
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 865 AA; 96675 MW; 9A92F4BCC14B796F CRC64;
MAASRSSRVT RSSVGLNGLD ENFCGRTLRN RSIAQPEETS VSPLPRARSP KKKQDNKQDT
KQESKHDAKQ ESKQDANSRK RGQSCLEKDI SPEKSENCDG GNGARDASPQ IKRAKRCSRS
GESQGQEKDP ELVKPESPVS VPELSKDNSC EELPNQNFAN TVPASPILSK QEGELIGDNA
EDGHVECDGA SQFPNAHKAS NGLRENNTEE SNTLGEKSSS NPTSDTNFPL LLNGSQTGTP
SSPDPAVPCR NSVPGHMEVS GSGELPSSSA PTSEVVLDDS VPELIVAKEQ EVEEMEVDVV
GDSFCLAHEE QVTESESDTN GRLLTPVTST SFTELYEHRY TRRTSPRRAV SSGKACSSKP
SSPPRDNGPL REEGEVVVGL EEEDCSMVEE PAPSDSIGHS NEEPVSGDPG DRAGGEDGGS
IEGKEAEHSK ELTQSQAAEE EEEEEEEEPD VYYFESDHLA LKHNKDYQRL LQTIGVLEAQ
RTQAILDLET LARHQREALA DPISFVEQLQ KRVNLGLPCP QHVVQLPDIA WEQYTSGLGD
FEREFCDKKR KTRRLKLIFD KGLPLRPKSP VEPKKEGESS TMYSPLPTSD APENGRQTQM
IRGRICHPNK PDTFNQLWTV EEQKKLEQLL VKFPPEEVES RRWQKIADEL GNRTAKQVAS
RVQKYFIKLT KAGIPVPGRT PNLCMYTKKA SSKRQHHLNK HLYRPSTFLT SYEPPVYMDE
DDERSAYYNS VQDPSADDSD EESVPVELRS LPEYKELLQL KRLKKQKLQE IQEDKTEIRH
IGYKCDVCGM EPILGVRWHC QDCPPDNSVD FCSNCSDCLL KTETHKPNHH LEPVYQAETF
LDRDYCLPQS TGYNYLDPNY FPANR
//
