ID   I3KS80_ORENI            Unreviewed;       374 AA.
AC   I3KS80;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 61.
DE   RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000023976.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000023976.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; I3KS80; -.
DR   Ensembl; ENSONIT00000023997.2; ENSONIP00000023976.2; ENSONIG00000034584.1.
DR   eggNOG; KOG1721; Eukaryota.
DR   GeneTree; ENSGT00950000182774; -.
DR   HOGENOM; CLU_002678_17_1_1; -.
DR   TreeFam; TF343410; -.
DR   Proteomes; UP000005207; Unplaced.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24404:SF49; RH47711P-RELATED; 1.
DR   PANTHER; PTHR24404; ZINC FINGER PROTEIN; 1.
DR   Pfam; PF00096; zf-C2H2; 4.
DR   SMART; SM00355; ZnF_C2H2; 5.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00042}.
FT   DOMAIN          210..237
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          257..284
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          285..312
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          313..340
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          341..368
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          127..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        137..160
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..175
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   374 AA;  43246 MW;  44B90C2D275CCC95 CRC64;
     MIKHCFYSRL KREYNHKLAK DFHSSQYSFI VSSNFYHIPR ILQGYNCLYN TLTPCVWLFS
     AEVQQLLEMK EDHPEWGLGL DQQDRESLQI KEEQEELWTN QEGEQHNGLK VTDVTTFPFT
     IVTVKSEDDD KEKSQSLQLH QSQTEDNNEM EPLTSSPAKQ VKTEPDEEDC GGPESKGNLD
     THIYLQPKTD VKASDSSETE GAFNTLKKSF SCSECDKEFL QKQSLQKHIT YHTKEKPLGC
     NVCEATFRQL HTDEKLFGCD ICGQRFNQKA HLKTHFRVHT GEKPFGCNVC EKRFGNQSNF
     NRHTRVHARE KPFSCGVFGE GFRHHCSLKT HQRVHTGEKP FGCGVCSKRF SNPGDLKRHQ
     SVHTVEKQFI LCYI
//