ID I3KZS8_ORENI Unreviewed; 474 AA.
AC I3KZS8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Tripartite motif-containing protein 35-like {ECO:0000313|Ensembl:ENSONIP00000026625.2};
GN Name=LOC100707901 {ECO:0000313|Ensembl:ENSONIP00000026625.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000026625.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000026625.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003448464.1; XM_003448416.4.
DR AlphaFoldDB; I3KZS8; -.
DR Ensembl; ENSONIT00000026649.2; ENSONIP00000026625.2; ENSONIG00000021323.2.
DR GeneID; 100707901; -.
DR KEGG; onl:100707901; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00970000193381; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR InParanoid; I3KZS8; -.
DR OMA; ERFDQHH; -.
DR OrthoDB; 5479648at2759; -.
DR TreeFam; TF334286; -.
DR Proteomes; UP000005207; Linkage group LG5.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd12893; SPRY_PRY_TRIM35; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF611; E3 UBIQUITIN-PROTEIN LIGASE TRIM39-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 11..51
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 83..124
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 273..463
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 474 AA; 54582 MW; C7DB3CBD472F030F CRC64;
MSSQSEMNLS CSICYDIFRD PIMLSCSHSF CKDCLQMWWK EKPVRKCPLC KNLHLSDDPP
CNLVLKNLCE AFLLEKAQKA SLESEAHCSL HSEKLKLFCL DHQLPVCLVC RDSKIHNKHK
FRTIEEAAED HRKVLQVLLK PLKEKLKNFK IVKGEFDQTR EHIKIQALHT ERKIKEKFAK
MHQFLQEEEK ERITALRAEE EQKSQMIKEK TEALSRKIAA LLDTIRATEE YLRAEDVSFL
QNIKPAVNRV QQCTLLEELH VVSGALIDVA QHLGNLTFNI WKNMKEMVSC TPVILDPNTA
HQQLILSEDL TSVSLGERQQ LPNNPERFDH HPIVLGSEGF DSGTHSWDVE VRKDGIRCLG
VLIESVKRKE QLQTGFWEIC LQDGQYTAAA PPLPDKPLSV KKLQRVKVQL DCDRGKLSFF
DLDTSTHIHT FKLSFTEKLF PYIGTHNKVP MKILPVTVRV EQHTPSLSTG FWFS
//
