ID I3L0U8_HUMAN Unreviewed; 99 AA.
AC I3L0U8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Dynactin subunit 5 {ECO:0000256|ARBA:ARBA00034865};
DE Flags: Fragment;
GN Name=DCTN5 {ECO:0000313|Ensembl:ENSP00000458354.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000458354.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000458354.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
RN [2] {ECO:0007829|PubMed:21269460}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [3] {ECO:0000313|Ensembl:ENSP00000458354.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynactin subunits 5/6 family. Dynactin
CC subunit 5 subfamily. {ECO:0000256|ARBA:ARBA00034706}.
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DR EMBL; AC008870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3L0U8; -.
DR SMR; I3L0U8; -.
DR MassIVE; I3L0U8; -.
DR PeptideAtlas; I3L0U8; -.
DR ProteomicsDB; 46454; -.
DR Antibodypedia; 43088; 126 antibodies from 20 providers.
DR Ensembl; ENST00000566298.1; ENSP00000458354.1; ENSG00000166847.10.
DR UCSC; uc059sdl.1; human.
DR HGNC; HGNC:24594; DCTN5.
DR VEuPathDB; HostDB:ENSG00000166847; -.
DR GeneTree; ENSGT00390000015360; -.
DR OMA; SQIHGTQ; -.
DR ChiTaRS; DCTN5; human.
DR Proteomes; UP000005640; Chromosome 16.
DR Bgee; ENSG00000166847; Expressed in islet of Langerhans and 201 other cell types or tissues.
DR ExpressionAtlas; I3L0U8; baseline and differential.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR CDD; cd03359; LbH_Dynactin_5; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR047125; DCTN5.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR PANTHER; PTHR46126; DYNACTIN SUBUNIT 5; 1.
DR PANTHER; PTHR46126:SF1; DYNACTIN SUBUNIT 5; 1.
DR Pfam; PF21711; DCTN5; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:I3L0U8,
KW ECO:0007829|PeptideAtlas:I3L0U8};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT NON_TER 99
FT /evidence="ECO:0000313|Ensembl:ENSP00000458354.1"
SQ SEQUENCE 99 AA; 10960 MW; D8CF469C6A4381AC CRC64;
MNDCIIRGDL ANVRVGRHCV VKSRSVIRPP FKKFSKGVAF FPLHIGDHVF IEEDCVVNAA
QIGSYVHVGK NCVIGRRCVL KDCCKILDNT VLPPETVVP
//
