ID I3L1U4_HUMAN Unreviewed; 114 AA.
AC I3L1U4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Serpin family F member 1 {ECO:0000313|Ensembl:ENSP00000459107.1};
GN Name=SERPINF1 {ECO:0000313|Ensembl:ENSP00000459107.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000459107.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000459107.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000459107.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC130343; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC130689; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3L1U4; -.
DR SMR; I3L1U4; -.
DR MassIVE; I3L1U4; -.
DR MaxQB; I3L1U4; -.
DR PeptideAtlas; I3L1U4; -.
DR ProteomicsDB; 46747; -.
DR Ensembl; ENST00000573770.5; ENSP00000459107.1; ENSG00000132386.11.
DR UCSC; uc059zje.1; human.
DR HGNC; HGNC:8824; SERPINF1.
DR VEuPathDB; HostDB:ENSG00000132386; -.
DR GeneTree; ENSGT00940000158112; -.
DR HOGENOM; CLU_170461_0_0_1; -.
DR ChiTaRS; SERPINF1; human.
DR Proteomes; UP000005640; Chromosome 17.
DR Bgee; ENSG00000132386; Expressed in pigmented layer of retina and 201 other cell types or tissues.
DR ExpressionAtlas; I3L1U4; baseline and differential.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR Pfam; PF00079; Serpin; 1.
DR SUPFAM; SSF56574; Serpins; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:I3L1U4,
KW ECO:0007829|PeptideAtlas:I3L1U4};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..114
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003675252"
FT DOMAIN 57..96
FT /note="Serpin"
FT /evidence="ECO:0000259|Pfam:PF00079"
FT REGION 20..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 114 AA; 12026 MW; 4E51BEAA66B8E5AB CRC64;
MQALVLLLCI GALLGHSSCQ NPASPPEEGS PDPDSTGALV EEEDPFFKVP VNKLAAAVSN
FGYDLYRVRS STSPTTNVLL SPLSVATALS ALSLGLMPLT YFRKISKDEN SLAT
//
