ID I3LKQ5_PIG Unreviewed; 537 AA.
AC I3LKQ5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Eukaryotic elongation factor, selenocysteine-tRNA specific {ECO:0000313|Ensembl:ENSSSCP00000024670.3};
GN Name=EEFSEC {ECO:0000313|Ensembl:ENSSSCP00000024670.3,
GN ECO:0000313|VGNC:VGNC:87558};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000024670.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000024670.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000024670.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000024670.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3LKQ5; -.
DR Ensembl; ENSSSCT00000031616.4; ENSSSCP00000024670.3; ENSSSCG00000011619.5.
DR VGNC; VGNC:87558; EEFSEC.
DR GeneTree; ENSGT00940000158170; -.
DR HOGENOM; CLU_083789_0_0_1; -.
DR TreeFam; TF300432; -.
DR Proteomes; UP000008227; Chromosome 13.
DR Bgee; ENSSSCG00000011619; Expressed in hindlimb bud and 44 other cell types or tissues.
DR ExpressionAtlas; I3LKQ5; baseline and differential.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd04094; eSelB_III; 1.
DR CDD; cd01889; SelB_euk; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR049394; eEFSec_C.
DR InterPro; IPR049393; eEFSec_III.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF11; SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR; 1.
DR Pfam; PF21131; eEFSec_4th; 1.
DR Pfam; PF21208; euk_SelB_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:I3LKQ5};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 5..215
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 323..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 58684 MW; E6654F3C7259C74C CRC64;
MAGRRVNVNV GVLGHIDSGK TALARALSTT ASTAAFDKQP QSRERGITLD LGFSCFSVPL
PERLRPAPPG TEPESGAELQ ITLVDCPGHA SLIRTIIGGA QIIDLMMLVI DVTKGMQTQS
AECLVIGQIA CQKLVVVLNK TDLLPEGKRQ AAIEKMTRKM QKTLENTKFR GAPIIPVAAR
PGGPEAPETE APQGIPELIE VVRKVKSMQM FHTPVTSAVQ GDRLGICVTQ FDPKLLERGL
VCAPESLHTV HAAVISVEKI PYFRGPLQTK AKFHITVGHE TVMGRVMFFS PAPDSFDHKP
VLDSFDFSQE YLFQEQYLCP SSAPAATDTT DSGGDDKKAG QASEGHCPRQ QWALVEFEKP
VTCPRLCLVI GSRLDADIHA NTCRLAFHGV LLHGLEDKNY AESCLPKLRV YKLKHKHGVV
ERVMDDYSVI GRSLFKKETN IQLFVGLKVH LSTGELGVID SAFGQSGKFK VHIPGGLSPE
SKKILTPALK KRGRAGRGEA AKQEEGAERL EPTQHVELSL SFKRYVFDTH KRMVQSP
//
