ID I3LPF1_PIG Unreviewed; 528 AA.
AC I3LPF1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Acyl-CoA binding domain containing 3 {ECO:0000313|Ensembl:ENSSSCP00000025978.2};
GN Name=ACBD3 {ECO:0000313|Ensembl:ENSSSCP00000025978.2,
GN ECO:0000313|VGNC:VGNC:95641};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000025978.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000025978.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000025978.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000025978.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3LPF1; -.
DR SMR; I3LPF1; -.
DR STRING; 9823.ENSSSCP00000025978; -.
DR PeptideAtlas; I3LPF1; -.
DR Ensembl; ENSSSCT00000029429.4; ENSSSCP00000025978.2; ENSSSCG00000024180.4.
DR VGNC; VGNC:95641; ACBD3.
DR eggNOG; KOG3878; Eukaryota.
DR GeneTree; ENSGT00530000063651; -.
DR HOGENOM; CLU_1427580_0_0_1; -.
DR InParanoid; I3LPF1; -.
DR Reactome; R-SSC-432722; Golgi Associated Vesicle Biogenesis.
DR Proteomes; UP000008227; Chromosome 10.
DR Bgee; ENSSSCG00000024180; Expressed in pituitary gland and 46 other cell types or tissues.
DR ExpressionAtlas; I3LPF1; baseline and differential.
DR Genevisible; I3LPF1; SS.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR GO; GO:0034237; F:protein kinase A regulatory subunit binding; IEA:Ensembl.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR InterPro; IPR022408; Acyl-CoA-binding_prot_CS.
DR InterPro; IPR000582; Acyl-CoA-binding_protein.
DR InterPro; IPR035984; Acyl-CoA-binding_sf.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR PANTHER; PTHR22973:SF11; GOLGI RESIDENT PROTEIN GCP60; 1.
DR PANTHER; PTHR22973; LD35087P; 1.
DR Pfam; PF00887; ACBP; 1.
DR Pfam; PF13897; GOLD_2; 1.
DR SUPFAM; SSF47027; Acyl-CoA binding protein; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS00880; ACB_1; 1.
DR PROSITE; PS51228; ACB_2; 1.
DR PROSITE; PS50866; GOLD; 1.
PE 1: Evidence at protein level;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Proteomics identification {ECO:0007829|PeptideAtlas:I3LPF1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 83..174
FT /note="ACB"
FT /evidence="ECO:0000259|PROSITE:PS51228"
FT DOMAIN 384..526
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..47
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 528 AA; 60720 MW; 4D68CCAC82F6C1FB CRC64;
MAAVLNAERL EVSVDGLTLS PDPEERPGAE GAPLLPPPLP PPSPPGSDRG RGAAGEQPEP
GEAAAGGAAE EARRLEQRWG FGLEELYGLA LRFFKEKDGK AFHPTYEEKL KLVALHKQVL
MGPYNPDTCP EVGFFDVLGN DRRREWAALG TMSKEDAMVE FVKLLNRCCH LFSTYVASHK
IEKEEQEKKR KEEEERRRRE EEERERLQKE EEKRRREEEE RLRREEEERR RIEEERLRLE
QQKQQIMAAL NSQTAVQFQQ YAAQQYPGNY EQQQILIRQL QEQHYQQYMQ QLYQVQLAQQ
QAALQKQQEV AVAGASLPTS SKVNTPAPGD MMSVNGQAKN HSDNSEKELE PETAEEALEN
GPKESLPVIA APSMWTRPQI RDFKEKIRQD SDSVITVGRG EVVTVRVPTH EEGSYLFWEF
ATDNYDIGFG VYFEWTDSPN TAVSVHVSES SDDDDEEEEN ISSEEKAKKN ANKPVLDEIV
PVYRRDCHEE VYAGSHQYPG RGVYLLKFDN SYSLWRSKSV YYRVYYTR
//
