ID I3LRX3_PIG Unreviewed; 285 AA.
AC I3LRX3; I6ZPE7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Luteinizing hormone/choriogonadotropin receptor {ECO:0000313|Ensembl:ENSSSCP00000026864.3};
GN Name=LHCGR {ECO:0000313|Ensembl:ENSSSCP00000026864.3,
GN ECO:0000313|VGNC:VGNC:110284};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000026864.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000026864.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000026864.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000026864.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; I3LRX3; -.
DR Ensembl; ENSSSCT00000023692.3; ENSSSCP00000026864.3; ENSSSCG00000008421.5.
DR VGNC; VGNC:110284; LHCGR.
DR GeneTree; ENSGT00940000157364; -.
DR HOGENOM; CLU_910731_0_0_1; -.
DR Proteomes; UP000008227; Chromosome 3.
DR Bgee; ENSSSCG00000008421; Expressed in ovary and 14 other cell types or tissues.
DR ExpressionAtlas; I3LRX3; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24372; GLYCOPROTEIN HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24372:SF1; LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..285
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023945784"
SQ SEQUENCE 285 AA; 31676 MW; DE748FA0BBE108D5 CRC64;
MRRRSLALRL LLALLLLPPP LPQTLLGAPC PEPCSCRPDG ALRCPGPRAG LSRLEISQSD
SLEKIEANAF DNLLNLSEIL IQNTKNLVYI EPGAFTNLPR LKYLSICNTG IRKLPDVTKI
FSSEFNFILE ICDNLHITTV PANAFQGMNN ESITLKLYGN GFEEIQSHAF NGTTLISLEL
KENAHLKKMH NDAFRGARGP SILDISSTKL QALPSYGLES IQTLIATSSY SLKKLPSREK
FTNLLDATLT YPSHCCAFRN LPTKENSEFK IVNWWTAPCP FTPCL
//
