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Database: UniProt
Entry: I3LWD7_ICTTR
LinkDB: I3LWD7_ICTTR
Original site: I3LWD7_ICTTR 
ID   I3LWD7_ICTTR            Unreviewed;      1817 AA.
AC   I3LWD7;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   25-APR-2018, entry version 51.
DE   SubName: Full=Kinesin family member 1B {ECO:0000313|Ensembl:ENSSTOP00000000283};
GN   Name=KIF1B {ECO:0000313|Ensembl:ENSSTOP00000000283};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel)
OS   (Spermophilus tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha;
OC   Sciuridae; Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000000283, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Ensembl:ENSSTOP00000000283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000000283}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00283, ECO:0000256|SAAS:SAAS00583243}.
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DR   EMBL; AGTP01079160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGTP01079161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGTP01079162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGTP01079163; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGTP01079164; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 43179.ENSSTOP00000000283; -.
DR   Ensembl; ENSSTOT00000000318; ENSSTOP00000000283; ENSSTOG00000000312.
DR   eggNOG; KOG0245; Eukaryota.
DR   eggNOG; COG5059; LUCA.
DR   GeneTree; ENSGT00890000139327; -.
DR   InParanoid; I3LWD7; -.
DR   OrthoDB; EOG091G009V; -.
DR   TreeFam; TF105221; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:1904115; C:axon cytoplasm; IEA:GOC.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:Ensembl.
DR   GO; GO:0005875; C:microtubule associated complex; IEA:Ensembl.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATPase activity; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:Ensembl.
DR   GO; GO:0008089; P:anterograde axonal transport; IEA:Ensembl.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; IEA:Ensembl.
DR   CDD; cd00060; FHA; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR022164; Kinesin-like.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR   InterPro; IPR032405; Kinesin_assoc.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR24115; PTHR24115; 1.
DR   Pfam; PF12473; DUF3694; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF12423; KIF1B; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   Pfam; PF16183; Kinesin_assoc; 1.
DR   Pfam; PF00169; PH; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00129; KISc; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|SAAS:SAAS00875240}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005215};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|SAAS:SAAS00874078};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT   DOMAIN        5    355       Kinesin motor. {ECO:0000259|PROSITE:
FT                                PS50067}.
FT   DOMAIN      557    613       FHA. {ECO:0000259|PROSITE:PS50006}.
FT   DOMAIN     1702   1800       PH. {ECO:0000259|PROSITE:PS50003}.
FT   COILED      366    386       {ECO:0000256|SAM:Coils}.
FT   COILED      471    491       {ECO:0000256|SAM:Coils}.
FT   COILED      676    703       {ECO:0000256|SAM:Coils}.
FT   COILED      712    732       {ECO:0000256|SAM:Coils}.
FT   COILED      843    863       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1817 AA;  204412 MW;  98A664F30C9335C5 CRC64;
     MSGASVKVAV RVRPFNSRET SKESKCIIQM QGNSTSIINP KNPKEAPKSF SFDYSYWSHT
     SPEDPCFASQ NRVYNDIGKE MLLHAFEGYN VCIFAYGQTG AGKSYTMMGK QEESQAGIIP
     QLCEELFEKI NDNCNEEMSY SVEVSYMEIY CERVRDLLNP KNKGNLRVRE HPLLGPYVED
     LSKLAVTSYT DIADLMDAGN KARTVAATNM NETSSRSHAV FTIVFTQKKH DSETNLSTEK
     VSKISLVDLA GSERADSTGA KGTRLKEGAN INKSLTTLGK VISALAEVDN CTSKVCKKKK
     KTDFIPYRDS VLTWLLRENL GGNSRTAMVA ALSPADINYD ETLSTLRYAD RAKQIKCNAV
     INEDPNAKLV RELKEEVTRL KDLLRAQGLG DIIDIDPLID DYSGSGGKYL KDFQNNKHRY
     LLASENQRPG NFSTASMGSL TSSPSSCSLS SQVGLTSVTS IQERIMSTPG GEEAIERLKE
     SEKIIAELNE TWEEKLRKTE AIRMEREALL AEMGVAIRED GGTLGVFSPK KTPHLVNLNE
     DPLMSECLLY YIKDGITRVG QADAERRQDI VLSGAHIKEE HCIFRSERNN SGEVIVTLEP
     CERSETYVNG KRVTQPVQLR SGNRIIMGKN HVFRFNHPEQ ARAEREKTPS AETPSEPVDW
     TFAQRELLEK QGIDMKQEME KRLQEMEILY KKEKEEADLL LEQQRLDYES KLQALQKQVE
     TRSLAAETTE EEEEEEEVPW TQHEFELAQW AFRKWKSHQF TSLRDLLWGN AVYLKEANAI
     SVELKKKVQF QFVLLTDTLY SPLPPELLPT EVDKTHEERP FPRTVVAVEV QDLKNGATHY
     WSLEKLKQRL DLMREMYDRA GEMVSNAQDD SEATMTGSDP FYDRFHWFKL VGSSPIFHGC
     VNERLADRTP SPTFSTADSD ITELADEQQD EMEDFDDEAF VDDTGSDAGT EEGSDLFSDG
     HDPFYDRSPW FILVGRAFVY LSNLLYPVPL IHRVAIVSEK GEVRGFLRVA VQAIAADEEA
     PDYGSGIRQS GTAKISFDNE YFNQSDFSSV AMTRSGLSLE ELRIVEGQGQ SSEVITPPEE
     ISRTNDLDLK SSTLLDGKMV MEGFSEEIGN HLKLGSAFTF RVTVLQASGI LPEYADIFCQ
     FNFLHRHDEA FSTEPLKNNG RGSPLGFYHV QNIAVEVTES FVDYIKTKPI VFEVFGHYQQ
     HPLHLQGQDL NSPPQPSRRF FPPPMPLSRP VPATKLNTMS KTSLGQSMSK YDLLVWFEIS
     ELEPTGEYIP AVVDHTAGLP CQGTFLLHQG IQRRITVTII HEKGSELHWK DVRELVVGRI
     RNKPEVDEAA IDAILSLNII SAKYLKSSHN SSRTFYRFEA VWDSSLHNSL LLNRVTPYGE
     KIYMTLSAYL ELDHCIQPAV VTKDVCMVFY SRDAKISPPR SLRSLFGSGY SKSPDSNRVT
     GIYELSLCKM ADTGSPGMQR RRRKVLDTSV AYVRGEENLA GWRPRGDSLI LEHQWELEKL
     ELLHEVEKTR HFLLLRERLG DSIPKSLSDS LSPSLSSGTL STSTSISSQI STTTFESAIT
     PSESSGYDSA DIESLVDREK ELATKCLQLL THTFNREFNQ VHGSISDCKL SDISPIGRDP
     SVSSFSSATL TPSSTCPSLV DSRSNSADQK TPEANSRASS PCPEFEQFQI VPAVETPYLA
     RAGKNEFLNL VPDIEEIRPG SVVSKKGYLH FKEPLSSNWA KHFVVVRRPY VFIYNSDKDP
     VERGIINLST AQVEYSEDQQ AMVKTPNTFA VCTKHRGVLL QALNDKDMND WLYAFNPLLA
     GTIRSKLSRR CTSQPKY
//
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