ID I3LYV7_ICTTR Unreviewed; 337 AA.
AC I3LYV7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Oxoglutarate receptor 1 {ECO:0000313|Ensembl:ENSSTOP00000001429.2};
GN Name=OXGR1 {ECO:0000313|Ensembl:ENSSTOP00000001429.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000001429.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000001429.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AGTP01004478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005317087.1; XM_005317030.1.
DR AlphaFoldDB; I3LYV7; -.
DR STRING; 43179.ENSSTOP00000001429; -.
DR Ensembl; ENSSTOT00000001598.3; ENSSTOP00000001429.2; ENSSTOG00000001603.3.
DR GeneID; 101976293; -.
DR CTD; 27199; -.
DR eggNOG; ENOG502QYYG; Eukaryota.
DR GeneTree; ENSGT01030000234621; -.
DR HOGENOM; CLU_009579_8_2_1; -.
DR InParanoid; I3LYV7; -.
DR OMA; FVIIHPM; -.
DR OrthoDB; 3788900at2759; -.
DR TreeFam; TF330775; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:Ensembl.
DR CDD; cd15375; 7tmA_OXGR1; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24231:SF15; 2-OXOGLUTARATE RECEPTOR 1; 1.
DR PANTHER; PTHR24231; PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01157; P2YPURNOCPTR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..302
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 337 AA; 38202 MW; 8AC089549FD9273C CRC64;
MNEPLDGLAN ASDFPDYAAA FGNCTDEKIS LKMHYLPVIY GIIFLVGFPG NAVAISTYIF
KMRPWRSSTI IMLNLACTDL LYLTSLPFLI HYYASGENWI FGEFMCKFIR FGFHFNLYSS
ILLLTCFSIF RYIVIIHPMS CFSIHKTRWT VVACAVVWII SLVAVMPMTF LITSTNMTNR
STCLDLTSSD DLTTIKWYNL ILTATTFCLP LVIVTLCYTT IINTLTHGPQ TQSCLKQKAR
RLTILLLLVF YICFLPFHVL RVIRIESRLL SISCSIENQI HEAYIVSRPL AALNTFGNLL
LYVVVSNNFQ QAICSIVRCK ESGDLEQAKK VSCSNNP
//
