ID I3LZ58_ICTTR Unreviewed; 1111 AA.
AC I3LZ58;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Solute carrier family 9 member C1 {ECO:0000313|Ensembl:ENSSTOP00000001570.3};
GN Name=SLC9C1 {ECO:0000313|Ensembl:ENSSTOP00000001570.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000001570.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000001570.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01111506; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111507; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111508; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111509; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111510; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111511; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111512; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111513; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111514; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01111515; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3LZ58; -.
DR STRING; 43179.ENSSTOP00000001570; -.
DR Ensembl; ENSSTOT00000001759.3; ENSSTOP00000001570.3; ENSSTOG00000001747.3.
DR GeneTree; ENSGT00940000162055; -.
DR HOGENOM; CLU_003400_1_0_1; -.
DR InParanoid; I3LZ58; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:Ensembl.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR GO; GO:0030317; P:flagellated sperm motility; IEA:Ensembl.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10110; SODIUM/HYDROGEN EXCHANGER; 1.
DR PANTHER; PTHR10110:SF87; SODIUM_HYDROGEN EXCHANGER 10; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 38..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 579..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..625
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 854..948
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 1111 AA; 129474 MW; 722665E32BA39766 CRC64;
MDEYGVHINV TFYNKLPGTW MEFFKTVLLS TPKDLPEIIL VLSLICAIGA FLNMHLKDFP
IPLPVILFLI GCSFEILSFT SFQIQRYADA IQWMNPELFF GIFTPVIIFN VAYDMDVYML
QKLFWQILLI TIPGFVINYV LILWYLQSVN KLLLKTIPWL LFAVILMSSD PMLTAAAIRD
LGLSRALTNL ISGESLMTSV ISIIVFSTIV NINFKRQYSK LRGRALAYYI YMLTYIFFHL
WQKFVFLLIL FFPFLTKGEL VEMSGIFTLA IMGLFLNSTS FKPGVEALLL EFWNCISFVA
FLMVFKRNDI FFSLLLVFIM MSPILSRLGH GFSWRWAFIM VWSEMKGTPN ISMALLVAYS
NFSVGTEREK SQVLFHGVLV CLINLIINRF ILPMAVTKLG LRDVTSTKYK SVYYTFQHFQ
ELTKSTASAL KFDKDLANAD WNMVEKAIVL QNPYALKQGE TTEHQKVVCP DCNKEINETL
NIEAVKLANR RLLSAQIVST LSYRHSVLVE YKTQTLLFNY PYMTPETIKH YSESKKLLSF
LRKVLLNWVY NTKKDKGIPS RYCFLRLCHK IVFTDEFEYI GYLVVLMNIF PIIISWISQL
NDIYEHEIRF TNYYFLAFYI LEDLLKMAAM RKDYFSHTWN IFESVISLIG IIDIILTETN
FINYYLNFIE AKVIFMKIVR LLRILRILKL ITPKLLQIID KRMSHQLSFR YAILKGYVQG
EADVMNIIDR IASSEQIKQM LLIQVTSNME QAMKELGYLE YDHPEIAVTM KTKDEINVML
NMAREIVKAF RLEGILHKIE GAEIFKVIMA KKREVLDFQS VIKPLTVDET MYHIPWLEKD
KDRIDFIQER AKIVTFDCGN DIFEEGDEPK GIYIIISGMV KLKRVNLGTE NETILLETEE
KAYPVIYTDY VLSGEIIGEL NCLTNEPMKY SATCKTVVET YFIPKSHLYE AFRQKYPGME
DKMWLKIGRG ITAQKIREHL SYEDWNYKMQ LELYNMHIRD IPKNTKIGIY DESVTYVILI
HGAVEDCLSR KLYKAPFLIP ITCHQIQGIE DFTKIMIIQT SIDLEKHTWN TRKYMSTPKT
SLKLGSISEE HNKGQFNEEI ESEMQKNVQG C
//
