ID I3M241_ICTTR Unreviewed; 510 AA.
AC I3M241;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Solute carrier family 7 member 7 {ECO:0000313|Ensembl:ENSSTOP00000002991.3};
GN Name=SLC7A7 {ECO:0000313|Ensembl:ENSSTOP00000002991.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000002991.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000002991.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGTP01099398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01099399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01099400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01099401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01099402; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_013219955.1; XM_013364501.1.
DR AlphaFoldDB; I3M241; -.
DR STRING; 43179.ENSSTOP00000002991; -.
DR Ensembl; ENSSTOT00000003342.3; ENSSTOP00000002991.3; ENSSTOG00000003328.3.
DR eggNOG; KOG1287; Eukaryota.
DR GeneTree; ENSGT00940000160134; -.
DR HOGENOM; CLU_007946_3_5_1; -.
DR InParanoid; I3M241; -.
DR OrthoDB; 1103451at2759; -.
DR TreeFam; TF313355; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:Ensembl.
DR GO; GO:0015174; F:basic amino acid transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:1903826; P:L-arginine transmembrane transport; IEA:Ensembl.
DR GO; GO:0015820; P:leucine transport; IEA:Ensembl.
DR GO; GO:0000821; P:regulation of arginine metabolic process; IEA:Ensembl.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11785:SF303; Y+L AMINO ACID TRANSPORTER 1; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022970}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 510 AA; 55729 MW; D1818A0B00423996 CRC64;
MVDSIKYEVA SQQEADDSPL GHGASPGAQQ IKLKKEISLL NGVCLIVGNM IGSGIFVSPK
GVLMYSASFG LSLVIWAVGG LFSVFGALCY AELGTTIKKS GASYAYILEA FGGLLAFIRL
WTSLLIIEPT SQAIIAITFA NYMVQPLFPS CNAPYAAGRL LAAACICLLT FVNCAYVKWG
TLVQDIFTYA KVSALIAVII AGIVKLGQGA TTNLENSFKG SSFVMGDIAL ALYSALFSYS
GWDTLNYVTE ELKNPERNLP LSIGISMPLV TIIYILTNVA YYTVLNMRDI LASDAVAVTF
ADQIFGIFNW TIPLAVALSC FGGLNASIVA ASRLFFVGSR EGHLPDAICM IHVERFTPVP
SLLFNGIMAL IYLCVEDIFQ LINYYSFSYW FFVGLSIVGQ LYLRWKEPDR PRPLKLSIFF
PIVFCLCTVF LVAVPLYSDT INSLIGIGIA LSGLPFYFLI IRVPEDKRPL CLRRTLASAT
WYLQVLCMSV AAEMDLEDAE IPKQQDPKSN
//
