ID I3M4M0_ICTTR Unreviewed; 724 AA.
AC I3M4M0;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Sorbin and SH3 domain containing 1 {ECO:0000313|Ensembl:ENSSTOP00000004167.3};
GN Name=SORBS1 {ECO:0000313|Ensembl:ENSSTOP00000004167.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000004167.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000004167.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01082212; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01082213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01082214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3M4M0; -.
DR Ensembl; ENSSTOT00000004645.3; ENSSTOP00000004167.3; ENSSTOG00000004612.3.
DR GeneTree; ENSGT00940000158658; -.
DR HOGENOM; CLU_003951_2_1_1; -.
DR TreeFam; TF320680; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR CDD; cd11919; SH3_Sorbs1_1; 1.
DR CDD; cd11922; SH3_Sorbs1_2; 1.
DR CDD; cd11916; SH3_Sorbs1_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR035606; SORBS1_SH3.
DR InterPro; IPR035610; SORBS1_SH3_1.
DR InterPro; IPR035611; SORBS1_SH3_2.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 192..249
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 483..542
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 557..618
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 663..724
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 81097 MW; 23E8FFB42D0D89BC CRC64;
MSSECDGTSK AVVNGLAPGS NGQDKDMDPT KICTGKGAVT LRASSSYREI PSSSPVSPQE
TPQHESKPDE WRLSSNADAN GNAQPSSLAA KGYRSVHPSL PADKPQGSSP LLNEVASSNT
GADSQASTPA SKPSSAYPST TIVNPTIVLL QHNRDPVSER SVGEQDSAPA QEKPTSPVRA
AEKRAKDDSR RVVKSAQDLS NVSTDEVGIP LRNTERSKDW YKTMFKQIHK LNRDDDSDLY
SPRYSFSEDT KSPLSVPRSK SEMNYIDGEK VVKRSATLPL PTRSSSLKSS PERNDWEPPD
KKVDTRKYRA EPKSIYEYQP GKSSVLTNEK MSRDISPEEI DLKNEPWYKF FSELEFGKPP
PKKIWDYTPG DCSILPREDR KSSAVSPSLD ISPEPPGYIY SSNFHAVKRE SDGAPGDLTS
LENERQIYKS VLEGGDIPLQ GLSGLKRPSS SASTKDSESP RHFIPADYLE STEEFIRRRH
DDKEMRPARA KFDFKAQTLK ELPLQKGDIV YIYKQIDQNW YEGEHHGRVG IFPRTYIELL
PPAEKAQPKK LTPVQVLEYG EAIAKFNFNG DTQVEMSFRK GERITLLRQV DENWYEGRIP
GTSRQGIFPI TYVDVIKRPL VKNPVDYIDL PYSSSPSRSA TASPQQPQAQ QRRVTPDRSQ
TSPDLFSYQA LYSYVPQNDD ELELRDGDIV DVMEKCDDGW FVGTSRRTRQ FGTFPGNYVK
PLYL
//
