ID   I3M727_ICTTR            Unreviewed;       608 AA.
AC   I3M727;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Kelch like family member 10 {ECO:0000313|Ensembl:ENSSTOP00000005353.2};
GN   Name=KLHL10 {ECO:0000313|Ensembl:ENSSTOP00000005353.2};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000005353.2, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Proteomes:UP000005215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000005353.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AGTP01023477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005321915.1; XM_005321858.1.
DR   AlphaFoldDB; I3M727; -.
DR   SMR; I3M727; -.
DR   STRING; 43179.ENSSTOP00000005353; -.
DR   Ensembl; ENSSTOT00000005985.3; ENSSTOP00000005353.2; ENSSTOG00000005983.3.
DR   GeneID; 101961796; -.
DR   CTD; 317719; -.
DR   eggNOG; KOG4441; Eukaryota.
DR   GeneTree; ENSGT00940000154664; -.
DR   HOGENOM; CLU_004253_14_1_1; -.
DR   InParanoid; I3M727; -.
DR   OMA; IETYDAR; -.
DR   OrthoDB; 5472491at2759; -.
DR   TreeFam; TF329218; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0048808; P:male genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   CDD; cd18450; BACK_KLHL10; 1.
DR   CDD; cd18240; BTB_POZ_KLHL10; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR030608; KLHL10_BTB/POZ.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   PANTHER; PTHR24412:SF272; KELCH-LIKE PROTEIN DIABLO; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 6.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   PRINTS; PR00501; KELCHREPEAT.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          39..106
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
SQ   SEQUENCE   608 AA;  68977 MW;  E7B8F1C4FF0DEF7A CRC64;
     MEMESTAAST RFHQPHMERK MSAMTCEIFN ELRLEGKLCD VVIKVNGFEF NAHKNILCSC
     SSYFRALFTS GWNNTEKKVY NIPGISPDMM KLIIEYAYTR TVPITPDNVE KLLAAADQFN
     IMGIVRGCCE FLKSELCLDN CIGICKFTDY YYCPELRQKA YMFILHNFEE MVKVSAEFLE
     LSVTELKDII EKDELNVKQE DAVFEAILKW ISHDPQNRKQ HISVLLPKVR LALMHAEYFM
     NNVKMNDYVK DSEECKPVII NALKAMYDLN MNGPSNSDFT NPLTRPRLPY AILFAIGGWS
     GGSPTNAIEA YDARADRWVN VTCEEESPRA YHGAAYLKGY VYIIGGFDSV DYFNSVKRFD
     PVKKTWHQVA PMHSRRCYVS VTVLSNFIYA MGGFDGYVRL NTAERYEPET NQWTLIAPMH
     EQRSDASATT LYGKVYICGG FNGNECLFTA EVYNTESNQW TVIAPMRSRR SGIGVIAYGE
     HVYAVGGFDG ANRLRSAEAY SPVANTWRTI PTMFNPRSNF GIEVVDDLLF VVGGFNGFTT
     TFNVECYDEK TDEWYDAHDM SIYRSALSCC VVPGLANVGE YAARRDNFTG LALRDEVKYS
     ASTSTLPV
//