ID I3M7I0_ICTTR Unreviewed; 263 AA.
AC I3M7I0;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Methyltransferase like 21C {ECO:0000313|Ensembl:ENSSTOP00000005577.3};
GN Name=METTL21C {ECO:0000313|Ensembl:ENSSTOP00000005577.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000005577.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000005577.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01004281; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005317062.1; XM_005317005.2.
DR AlphaFoldDB; I3M7I0; -.
DR STRING; 43179.ENSSTOP00000005577; -.
DR Ensembl; ENSSTOT00000006239.3; ENSSTOP00000005577.3; ENSSTOG00000006231.3.
DR GeneID; 101969717; -.
DR CTD; 196541; -.
DR eggNOG; KOG2793; Eukaryota.
DR GeneTree; ENSGT00940000156596; -.
DR HOGENOM; CLU_055721_0_0_1; -.
DR InParanoid; I3M7I0; -.
DR OrthoDB; 2902182at2759; -.
DR TreeFam; TF354267; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0031072; F:heat shock protein binding; IEA:Ensembl.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:Ensembl.
DR GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR GO; GO:0008628; P:hormone-mediated apoptotic signaling pathway; IEA:Ensembl.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF13; PROTEIN-LYSINE METHYLTRANSFERASE METTL21C; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
SQ SEQUENCE 263 AA; 29321 MW; 7B4DE3F6FA658DE1 CRC64;
MDVCLSSAQQ SLCLGEAPNS PGGWLEEEEG ALQEDGTGGP PGDANNRESA LRSLQKFVPT
DYASYTQEHY QFAGKKIVIQ ESIESYGAVV WPAATALCQY LEEHQEELNL QDAKILEIGA
GPGLVSIVAS ILGAQVTATD LPDVLGNLQY NLLKNTLKCT AHLPEVKELV WGQDLEQNFP
RAALHYDYVL ASDVVYHHYF LDKLLLTMVH LSQQGTVILW ANKFRFSTDY EFLDKFKQVF
DTTLLAEYPE STVKLFKGTL KWD
//
