ID I3M9U4_ICTTR Unreviewed; 534 AA.
AC I3M9U4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Gigaxonin {ECO:0000313|Ensembl:ENSSTOP00000006691.3};
GN Name=GAN {ECO:0000313|Ensembl:ENSSTOP00000006691.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000006691.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000006691.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01010373; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3M9U4; -.
DR STRING; 43179.ENSSTOP00000006691; -.
DR Ensembl; ENSSTOT00000007488.3; ENSSTOP00000006691.3; ENSSTOG00000007492.3.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000155273; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; I3M9U4; -.
DR TreeFam; TF328485; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR CDD; cd18455; BACK_KLHL16_gigaxonin; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030579; KLHL16_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF232; GIGAXONIN; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 78..180
FT /note="BACK"
FT /evidence="ECO:0000259|SMART:SM00875"
SQ SEQUENCE 534 AA; 60925 MW; A4751F531F5E2764 CRC64;
TKLNYNPPKD DGSTYKIELE GISVMVMREI LDYIFSGQIR LNEDTIQDVV QAADLLLLTD
LKTLCCEFLE GCIAAENCIG IRDFALHYCL HHVHYLATEY LETHFRDVSS TEEFLELSPQ
KLKEVISLEK LNVGNERYVF EAVIRWIAHD TEIRKVHMKD VMSALWVSGL DSSYLREQML
NEPLVREIVK ECSNIPLSQP QQGEAMLANF KPRGYSECIV TVGGEERVSR KPTAAMRCMC
PLYDPNRQLW IELAPLSMPR INHGVLSAEG FLFVFGGQDE NKQTLSSGEK YDPDANTWTA
LPPMNEARHN FGIVEIDGML YILGGEDGEK ELISMECYDI YSKTWTKQPD LTMVRKIGCY
AAMKKKIYAM GGGSYGKLFE SVECYDPRTQ QWTAICPLKE RRVAMELYVF GGVRSREDIQ
GGEMVTCKSE FYHDEFKRWI YLNDQNLCIP ASSSFVYGAV PIGASIYVIG DLDTGTNYDY
VREFKRSTGT WHHTKPLLPS DLRRTGCAAL RIANCKLFRL QLQQGLFRIR VHSP
//
