ID I3MD94_ICTTR Unreviewed; 583 AA.
AC I3MD94;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Matrilin 4 {ECO:0000313|Ensembl:ENSSTOP00000008327.3};
GN Name=MATN4 {ECO:0000313|Ensembl:ENSSTOP00000008327.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000008327.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000008327.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01038492; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005325335.1; XM_005325278.1.
DR AlphaFoldDB; I3MD94; -.
DR Ensembl; ENSSTOT00000009281.3; ENSSTOP00000008327.3; ENSSTOG00000009281.3.
DR GeneTree; ENSGT00940000157086; -.
DR HOGENOM; CLU_008905_7_0_1; -.
DR TreeFam; TF330078; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0031012; C:extracellular matrix; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd01475; vWA_Matrilin; 1.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..583
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011648583"
FT DOMAIN 36..215
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 347..522
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 583 AA; 64159 MW; CB91C2740F0D4D95 CRC64;
MRGLLCWPLA TLLLLLQPWE TQQQPTGPKC HTGPLDLVFV IDSSRSVRPF EFETMRQFLV
GLLRSLDVGL NATRVGVIQY SSQVQSVFPL GAFSRREDME RAIRALVPLA QGTMTGLAIQ
YAMNVAFSEA EGARPPKERV PRVAVIVTDG RPQDRVAEVA AQARARGIEI YAVGVQRADV
GSLRAMASPP LDEHVFLVES FDLIQEFGLQ LQGRLCAIDL CAEGTHGCDH HCVSSPGSYF
CRCRAGFVLQ EDQRSCRAIN HCGFGNHSCE HECVSTLGGP RCRCREGHVL LPDGRTCQVR
DLCNGVDHGC EFQCVSKGLS YRCLCPEGRR LQADGKSCLR CREGHVDLVL LVDGSKSVRP
QNFELVKRFV NQIVDFLDVS PEGTRIGLVQ FSSRVRTEFP LGRYGTAAEV KQAVLAVEYM
ERGTMTGLAL RHMVEHSFSE AQGARPRALN VPRVGLVFTD GRSQDDISVW AARAKEEGIV
MYAVGVGKAV EEELREIASE PAELHVSYSP DFSTMTHLLE NLKGSICPEE GISAGTELRS
LCECESLVEF QGRTLGALEG LTQNLAQLTA RLEDLENQLA NKK
//
