ID I3MDM3_ICTTR Unreviewed; 323 AA.
AC I3MDM3;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Solute carrier family 25 member 27 {ECO:0000313|Ensembl:ENSSTOP00000008499.2};
GN Name=SLC25A27 {ECO:0000313|Ensembl:ENSSTOP00000008499.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000008499.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000008499.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; AGTP01010742; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01010743; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005318662.1; XM_005318605.2.
DR AlphaFoldDB; I3MDM3; -.
DR STRING; 43179.ENSSTOP00000008499; -.
DR Ensembl; ENSSTOT00000009476.3; ENSSTOP00000008499.2; ENSSTOG00000009477.3.
DR GeneID; 101971455; -.
DR CTD; 9481; -.
DR eggNOG; KOG0753; Eukaryota.
DR GeneTree; ENSGT00940000160098; -.
DR HOGENOM; CLU_015166_14_2_1; -.
DR InParanoid; I3MDM3; -.
DR OMA; FPFWKAV; -.
DR OrthoDB; 5488094at2759; -.
DR TreeFam; TF354328; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-KW.
DR GO; GO:0015108; F:chloride transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0015078; F:proton transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45618; MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED; 1.
DR PANTHER; PTHR45618:SF8; MITOCHONDRIAL UNCOUPLING PROTEIN 4; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transport {ECO:0000256|RuleBase:RU000488}.
FT REPEAT 21..115
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 125..217
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 226..317
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 323 AA; 35993 MW; 461FD22B6019D264 CRC64;
MSNPEDEERL LPLAQRWPRA SKFILSGCAA TVAELATFPL DLTKTRLQMQ GEAALARLGD
NARESAPYRG MVRTALGIIQ EEGFLKLWQG VTPAIYRHVV YSGGRMVTYE HLREVVFGKS
EDKHYPLWKS VIGGMMAGVI GQFLANPADL VKVQMQMEGK RKLEGKPLRF RGVHHAFAKI
LAEGGIRGLW AGWVPNIQRA ALVNMGDLTT YDTVKHYLIL NTPLKDNIIT HGLSSLCSGL
VASVLGTPAD VIKSRIMNQP RDKQGRGLLY KSSSDCLIQA VQGEGFMSLY KGFLPAWLRM
TPWSLVFWLT YEKIREMSGV SPF
//
