ID I3MDU2_ICTTR Unreviewed; 279 AA.
AC I3MDU2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=RAD1 checkpoint DNA exonuclease {ECO:0000313|Ensembl:ENSSTOP00000008602.2};
GN Name=RAD1 {ECO:0000313|Ensembl:ENSSTOP00000008602.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000008602.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000008602.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the rad1 family.
CC {ECO:0000256|ARBA:ARBA00010991}.
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DR EMBL; AGTP01040492; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005325700.1; XM_005325643.2.
DR RefSeq; XP_013214227.1; XM_013358773.1.
DR AlphaFoldDB; I3MDU2; -.
DR STRING; 43179.ENSSTOP00000008602; -.
DR Ensembl; ENSSTOT00000009589.3; ENSSTOP00000008602.2; ENSSTOG00000009593.3.
DR GeneID; 101964465; -.
DR CTD; 5810; -.
DR eggNOG; KOG3194; Eukaryota.
DR GeneTree; ENSGT00500000044913; -.
DR HOGENOM; CLU_035332_2_1_1; -.
DR InParanoid; I3MDU2; -.
DR OMA; WSQAYKF; -.
DR OrthoDB; 5473594at2759; -.
DR TreeFam; TF101211; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0030896; C:checkpoint clamp complex; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0071479; P:cellular response to ionizing radiation; IEA:Ensembl.
DR GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:Ensembl.
DR GO; GO:0051598; P:meiotic recombination checkpoint signaling; IEA:Ensembl.
DR CDD; cd00577; PCNA; 1.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR003011; Cell_cycle_checkpoint_Rad1.
DR InterPro; IPR046938; DNA_clamp_sf.
DR InterPro; IPR003021; Rad1_Rec1_Rad17.
DR PANTHER; PTHR10870; CELL CYCLE CHECKPOINT PROTEIN RAD1; 1.
DR PANTHER; PTHR10870:SF0; CELL CYCLE CHECKPOINT PROTEIN RAD1; 1.
DR Pfam; PF02144; Rad1; 1.
DR PRINTS; PR01245; RAD1REC1.
DR PRINTS; PR01246; RAD1REPAIR.
DR SUPFAM; SSF55979; DNA clamp; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
SQ SEQUENCE 279 AA; 31431 MW; 24D02E4BC67860CA CRC64;
MPLLTQQIQD ENENSLVASL DNVRNLSTIL KAIHFKDFAT CFATKNGIKV TVENAKCVQA
NAFIQAEIFQ EFVVQEESVT FRINLTVLLD CLSIFGSSPM PGTLTALRMC YQGYGHPLML
FLEEGGVVTV CKINTQEPEE TLDFDFCSTN VINKIILQSE GLREAFSELD MTSEVLQITM
SPNKPYFRLS TFGNAGSSHL DYPKDSDLME AFHCNQTQVN RYKISLLKPS TKALVLSCKV
SIRTDNRGFL SLQYMIRNED GQICFVEYYC CPDEEVPES
//
