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Database: UniProt
Entry: I3MDY0_ICTTR
LinkDB: I3MDY0_ICTTR
Original site: I3MDY0_ICTTR 
ID   I3MDY0_ICTTR            Unreviewed;       506 AA.
AC   I3MDY0;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   25-APR-2018, entry version 42.
DE   SubName: Full=Potassium voltage-gated channel subfamily C member 4 {ECO:0000313|Ensembl:ENSSTOP00000008649};
GN   Name=KCNC4 {ECO:0000313|Ensembl:ENSSTOP00000008649};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel)
OS   (Spermophilus tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha;
OC   Sciuridae; Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000008649, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Ensembl:ENSSTOP00000008649}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000008649}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
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DR   EMBL; AGTP01096672; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005338172.2; XM_005338115.2.
DR   STRING; 43179.ENSSTOP00000008649; -.
DR   Ensembl; ENSSTOT00000009640; ENSSTOP00000008649; ENSSTOG00000009645.
DR   eggNOG; KOG3713; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   InParanoid; I3MDY0; -.
DR   OrthoDB; EOG091G0EJL; -.
DR   TreeFam; TF352511; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0043679; C:axon terminus; IEA:Ensembl.
DR   GO; GO:0031594; C:neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003974; K_chnl_volt-dep_Kv3.
DR   InterPro; IPR028325; VG_K_chnl.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01498; SHAWCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005215};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00984201}.
FT   TRANSMEM    162    183       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    195    213       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    263    284       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    305    322       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    334    363       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      108    362       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   506 AA;  55897 MW;  3A8BD7243B230927 CRC64;
     ADVCGPLFEE ELTFWGIDET DVEPCCWMTY RQHRDAEEAL DIFESPDGGG GGAGPSDEVG
     DDERELALQR LGPHEGGGGP GAGSGGCRGW QPRMWALFED PYSSRAARVV AFASLFFILV
     SITTFCLETH EAFNIDRNVT EIHRVGNITS VRFRREVETE PILTYIEGVC VLWFTLEFLV
     RIVCCPDTLD FVKNLLNIID FVAILPFYLE VGLSGLSSKA ARDVLGFLRV VRFVRILRIF
     KLTRHFVGLR VLGHTLRAST NEFLLLIIFL ALGVLIFATM IYYAERIGAR PSDPRGNDHT
     DFKNIPIGFW WAVVTMTTLG YGDMYPKTWS GMLVGALCAL AGVLTIAMPV PVIVNNFGMY
     YSLAMAKQKL PKKRKKHVPR PPQLESPIYC KSEETSPRDS TYSDTSPPAR EEGVVERKRA
     DSKQNGDANA VLSDEEGAGL TQPLASAPTP EERRALRRSG TRDRNKKAAA CFLLSAGDYA
     CADGSVRKEG NVEPKACVPV SHTCAL
//
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