ID I3MFX2_ICTTR Unreviewed; 449 AA.
AC I3MFX2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Interferon related developmental regulator 1 {ECO:0000313|Ensembl:ENSSTOP00000009570.2};
GN Name=IFRD1 {ECO:0000313|Ensembl:ENSSTOP00000009570.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000009570.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000009570.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IFRD family.
CC {ECO:0000256|ARBA:ARBA00008828}.
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DR EMBL; AGTP01107894; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005340475.1; XM_005340418.2.
DR AlphaFoldDB; I3MFX2; -.
DR STRING; 43179.ENSSTOP00000009570; -.
DR Ensembl; ENSSTOT00000010659.3; ENSSTOP00000009570.2; ENSSTOG00000010658.3.
DR GeneID; 101972916; -.
DR CTD; 3475; -.
DR eggNOG; KOG2842; Eukaryota.
DR GeneTree; ENSGT00390000013347; -.
DR HOGENOM; CLU_031384_1_0_1; -.
DR InParanoid; I3MFX2; -.
DR OMA; CLGVCCF; -.
DR OrthoDB; 74891at2759; -.
DR TreeFam; TF313638; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0016528; C:sarcoplasm; IEA:Ensembl.
DR GO; GO:0042692; P:muscle cell differentiation; IEA:Ensembl.
DR GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR GO; GO:0048671; P:negative regulation of collateral sprouting; IEA:Ensembl.
DR GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
DR GO; GO:0014706; P:striated muscle tissue development; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039777; IFRD.
DR InterPro; IPR006921; Interferon-rel_develop_reg_C.
DR InterPro; IPR007701; Interferon-rel_develop_reg_N.
DR PANTHER; PTHR12354; INTERFERON-RELATED DEVELOPMENTAL REGULATOR; 1.
DR PANTHER; PTHR12354:SF6; INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1; 1.
DR Pfam; PF05004; IFRD; 1.
DR Pfam; PF04836; IFRD_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 48..345
FT /note="Interferon-related developmental regulator N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF05004"
FT DOMAIN 390..443
FT /note="Interferon-related developmental regulator C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04836"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 50061 MW; E4B795AC260E16EE CRC64;
MPKNKKRNTP HRGGSGGGGG GSGAAAATAG GQHRNVQPFS DEDASIETMS HCSGYSDPSS
FAEDGPEVLD EEGTQEDLEY KLKGLIDLTL DKSVKTRQAA LEGIKNVLAS KMFYEFILER
RMTLTDSIER CLKKGKSDEQ RAAAALASVL CIQLGPGIES EEILKTLGPV LKKIICDGTA
SIQARQACAT SFGICSFIAT DDITELYSTL ECLENIFTKS YLKEKDSNVI CSTPNTVLHI
SSLLAWTLLL TICPINEVKK KLEMHFHKLP SLLSCDDVNM RIAAGESLAL LFELARGMES
DFFYEDMESL TQMLRALATD GNKHRAKVDK RKQRSVFRDV LRAVEERDFP TETVKFGPER
MYIDSWVKKH TYDTFKEVLG SGMQYHLQSN EFLRNVFELG PPVLLDAATL KTMKISRFER
HLYNSAAFKA RTKARSKCRD KRTDVGEFF
//
