ID I3MH85_ICTTR Unreviewed; 89 AA.
AC I3MH85;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Non-histone chromosomal protein HMG-17 {ECO:0000256|ARBA:ARBA00040304};
DE AltName: Full=High mobility group nucleosome-binding domain-containing protein 2 {ECO:0000256|ARBA:ARBA00042290};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000010216.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000010216.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Binds to the inner side of the nucleosomal DNA thus altering
CC the interaction between the DNA and the histone octamer. May be
CC involved in the process which maintains transcribable genes in a unique
CC chromatin conformation. {ECO:0000256|ARBA:ARBA00037490}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HMGN family.
CC {ECO:0000256|ARBA:ARBA00007696}.
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DR EMBL; AGTP01061810; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3MH85; -.
DR STRING; 43179.ENSSTOP00000010216; -.
DR Ensembl; ENSSTOT00000011385.3; ENSSTOP00000010216.3; ENSSTOG00000011392.3.
DR GeneTree; ENSGT00950000182802; -.
DR HOGENOM; CLU_141985_0_2_1; -.
DR InParanoid; I3MH85; -.
DR OrthoDB; 4849681at2759; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031492; F:nucleosomal DNA binding; IEA:InterPro.
DR InterPro; IPR000079; HMGN_fam.
DR PANTHER; PTHR23087:SF13; NON-HISTONE CHROMOSOMAL PROTEIN HMG-17; 1.
DR PANTHER; PTHR23087; NONHISTONE CHROMOSOMAL PROTEIN HMG; 1.
DR Pfam; PF01101; HMG14_17; 1.
DR PRINTS; PR00925; NONHISHMG17.
DR SMART; SM00527; HMG17; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 89 AA; 9289 MW; 1378871BB469C490 CRC64;
MPKRKAEVDA TGDKAKVKDA RLSAKPAPPK PEPKPKKATA NKGEKVLKEK KGKAGPGKDE
NNPAENGVAK TDQAQKAGGA ADVKRSVSF
//
