ID I3MJ29_ICTTR Unreviewed; 1314 AA.
AC I3MJ29;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSSTOP00000011111.3};
GN Name=ZNF521 {ECO:0000313|Ensembl:ENSSTOP00000011111.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000011111.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000011111.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01055578; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01055579; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01055580; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 43179.ENSSTOP00000011111; -.
DR Ensembl; ENSSTOT00000012402.3; ENSSTOP00000011111.3; ENSSTOG00000012398.3.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000159287; -.
DR HOGENOM; CLU_004018_0_0_1; -.
DR InParanoid; I3MJ29; -.
DR TreeFam; TF331504; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 14.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406:SF23; FI01110P-RELATED; 1.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR Pfam; PF13912; zf-C2H2_6; 6.
DR Pfam; PF12874; zf-met; 2.
DR SMART; SM00355; ZnF_C2H2; 30.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 26.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 24.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 121..148
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 149..176
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 177..204
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 205..232
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 249..277
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 284..312
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 313..340
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 440..468
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 480..508
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 516..544
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 637..659
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 667..689
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 697..721
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 725..753
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 755..783
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 786..813
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 812..835
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 889..916
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 933..960
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 962..989
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1141..1169
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1228..1255
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1259..1287
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1289..1314
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 84..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 866..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1108..1128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1169..1191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1108..1124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1314 AA; 148125 MW; 69E44F72EA219120 CRC64;
MKPVFKPHTY SLGFLSDPNC KLEDKTEDGE AIDCKKRPED GEELEDEAVH SCDSCLQVFE
SLSDITEHKI NQCQLTDGVD VEDDPTCSWP ASSPSSKDQT SPSHGEGCDF GEEEGGPGLP
YPCQFCDKSF SRLSYLKHHE QSHSDKLPFK CTYCSRLFKH KRSRDRHIKL HTGDKKYHCS
ECDAAFSRSD HLKIHLKTHT SNKPYKCAIC RRGFLSSSSL HGHMQVHERN KDGSQSGSRM
EDWKMKDTQK CSQCEEGFDF PEDLQKHIAE CHPECSPNED RAALQCVYCH ELFVEETSLM
NHMEQVHSGE KKNSCSICSE SFHTVEELYS HMDSHQQPES CNHSNSPSLV TVGYTSVSST
TPDSNLSVDS STMVEAAPPI PKSRGRKRAA QQTPDMTGPS SKQAKVTYSC IYCNKQLFSS
LAVLQIHLKT MHLDKPEQAH ICQYCLEVLP SLYNLNEHLK QVHEAQDPGL IVSAMPAIVY
QCNFCSEVVN DLNTLQEHIR CSHGFANPAA KDSNAFFCPH CYMGFLTDSS LEEHIRQVHC
DLSSSRFGSP VLGTPKEPVV EVYSCSYCTN SPIFNSVLKL NKHIKENHKN IPLALNYIHN
GKKSRALSPL SPVAIEQTSL KMMQAVGGAP ARPTGEYICN QCGAKYTSLD SFQTHLKTHL
DTVLPKLTCP QCNKEFPNQE SLLKHVTIHF MITSTYYICE SCDKQFTSVD DLQKHLLDMH
TFVFFRCTLC QEVFDSKVSI QLHLAVKHSN EKKVYRCTSC NWDFRNETDL QLHVKHNHLE
NQGKVHKCIF CGESFGTEVE LQCHITTHSK KYNCKFCSKA FHAIILLEKH LREKHCVFET
KTPNCGTNGA SEQVQKEEVE LQTLLTNSQE SHNSHDGSEE DVDSSEPMYG CDICGAAYTM
ETLLQNHQLR DHNIRPGESA IVKKKAELIK GNYKCNVCSR TFFSENGLRE HMQTHLGPVK
HYMCPICGER FPSLLTLTEH KVTHSKSLDT GNCRICKMPL QSEEEFLEHC QMHPDLRNSL
TGFRCVVCMQ TVTSTLELKI HGTFHMQKTG NGSAVQTTGR GQHVQKLYKC ASCLKEFRSK
QDLVKLDING LPYGLCAGCV NLSKSSSPGI SLPPSTNRPG LGQNENLSAI EGKGKAGGLK
TRCSSCNVKF ESESELQNHI QTVHRELVPD SNSSQLKTPQ VSPMPRISPS QSDEKKTYQC
IKCQMVFYNE WDIQVHVANH MIDEGLNHEC KLCSQTFDSP AKLQCHLIEH SFEGMGGTFK
CPVCFTVFVQ ANKLQQHIFS AHGQEDKIYD CTQCPQKFFF QTELQNHTMT QHSS
//
