ID I3MKZ8_ICTTR Unreviewed; 338 AA.
AC I3MKZ8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=UDP-N-acetylglucosamine transporter {ECO:0000256|ARBA:ARBA00040900};
DE AltName: Full=Golgi UDP-GlcNAc transporter {ECO:0000256|ARBA:ARBA00041527};
DE AltName: Full=Solute carrier family 35 member A3 {ECO:0000256|ARBA:ARBA00041936};
GN Name=SLC35A3 {ECO:0000313|Ensembl:ENSSTOP00000012032.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000012032.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000012032.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35A
CC subfamily. {ECO:0000256|ARBA:ARBA00009976}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGTP01102601; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3MKZ8; -.
DR STRING; 43179.ENSSTOP00000012032; -.
DR Ensembl; ENSSTOT00000013427.3; ENSSTOP00000012032.3; ENSSTOG00000013428.3.
DR GeneTree; ENSGT00950000182827; -.
DR HOGENOM; CLU_024645_1_0_1; -.
DR InParanoid; I3MKZ8; -.
DR OrthoDB; 200085at2759; -.
DR TreeFam; TF315345; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005459; F:UDP-galactose transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:1990569; P:UDP-N-acetylglucosamine transmembrane transport; IEA:Ensembl.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR NCBIfam; TIGR00803; nst; 1.
DR PANTHER; PTHR10231; NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR10231:SF36; UDP-N-ACETYLGLUCOSAMINE TRANSPORTER; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR PIRSF; PIRSF005799; UDP-gal_transpt; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022597}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 338 AA; 37448 MW; A869D8A638D2858D CRC64;
MERLPLANED KTMSANLKYL SLGILVFQTT SLVLTMRYSR TLKEEGPRYL SSTAVVVAEL
LKIMACLLLV YKDSKCSLRA LNRVLHDEIL NKPMETLKLA IPSGIYTLQN NLLYVALSNL
DAATYQVTYQ LKILTTALFS VSMLSKKLGV YQWLSLVILM TGVAFVQWPS DSQEIDSKEL
SAGSQFVGLM AVLTACFSSG FAGVYFEKIL KETKQSVWIR NIQLGFFGSI FGLMGVYIYD
GELVSKNGFF QGYNRLTWIV VVLQALGGLV IAAVIKYADN ILKGFATSLS IILSTLISYF
WLQDFVPTSV FFLGAILVIA ATFLYGYDPK PAGNPIKA
//
