ID I3MPU4_ICTTR Unreviewed; 852 AA.
AC I3MPU4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=MET transcriptional regulator MACC1 {ECO:0000313|Ensembl:ENSSTOP00000013878.2};
GN Name=MACC1 {ECO:0000313|Ensembl:ENSSTOP00000013878.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000013878.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000013878.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AGTP01054350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005328850.1; XM_005328793.2.
DR AlphaFoldDB; I3MPU4; -.
DR STRING; 43179.ENSSTOP00000013878; -.
DR Ensembl; ENSSTOT00000015503.3; ENSSTOP00000013878.2; ENSSTOG00000015506.3.
DR GeneID; 101954826; -.
DR CTD; 346389; -.
DR eggNOG; ENOG502QZDM; Eukaryota.
DR GeneTree; ENSGT00390000013151; -.
DR HOGENOM; CLU_013080_1_0_1; -.
DR InParanoid; I3MPU4; -.
DR OMA; PPMLNHD; -.
DR OrthoDB; 4019548at2759; -.
DR TreeFam; TF105572; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 2.60.220.30; -; 1.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR15603:SF1; METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1; 1.
DR PANTHER; PTHR15603; SH3 DOMAIN-CONTAINING PROTEIN; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51145; ZU5; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 212..349
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 549..619
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 852 AA; 96762 MW; 83B35E634B84CDB5 CRC64;
MVISEIAHFW SGETTRSRAE GNLIDMEGEN LSKNCNITEW QDPGLLYNWP DAVTLQDDKA
LKVTNPFWKE LSASNPFLDD ITQQRNNQKK ENISILKEDP FLFLREIETG NSFDSSDDEL
DVHQLLSKSP LRKSGRSQSV SELLGILDDT TNTHQNMQDC DQILAQDLEW LQNDREAYKM
AWLSQRQLAR SCLDLNTMNQ SPGWAQTQVA ETITVCKLNH QGGSVQLPES DITVHVPQGH
VAVGEFQEVS LRAFLDPPQV LNNDLSCTVS PLLEIMLSNL NTMEAVLLEM KIGAEVRKDP
FSQVMTEMVC LHSLVKEGPF KVLNNCYVYK DTIQVKLVDL SKVMYLVIAA QPKAIQSPPA
TIWDYIHKTI SIGIYGPKYI HPNFTAIFTV CGHSYMPGKL TIPDIKKDGK STSPVVFQLW
GRHSFLLDKP QDLNISVFSC DPDFEVKVQG DGKQIKQKQL ESGEVVHQPL FFSLVDCREM
HLFVFRVQVE PPNGRPVAQF FITSPDPAPN LKRLSNLPGY LHKEKEDKST PLFSSVLVKY
PTFQDKKLNF SNYGVTLKTV LRQSKIDYFL EYFKGDTIAL LGEGKVKAMG QSKVKEWYVG
VLRGKIGLVH CKNVKVISKE QVMSVSDSIF TTRNLLEQIA LPFKKLTYIY SVVLTLVLEK
VYDWKVLAGV LGYSHLALEN FDQMQADKES EKVSYVVKKL KEDCHGDRNT RKFLYELIVA
LLKIDCQGLV VHLLQEAVIL TSAVKLGKCW RELAEKLVRL TKQQMEAYEI PHRGKTGDVA
AEMMWKPAYD FLYNWSAHYG NSYRDVLQDL QSALDRMKNP VTKQWRDLTG ALLLVNSLEI
LRVTAFSTSE DV
//
