ID I3MUA2_ICTTR Unreviewed; 319 AA.
AC I3MUA2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN Name=LOC101973224 {ECO:0000313|Ensembl:ENSSTOP00000015697.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000015697.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000015697.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; AGTP01124145; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01124146; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01124147; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01124148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01124149; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01124150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01124151; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01124152; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3MUA2; -.
DR STRING; 43179.ENSSTOP00000015697; -.
DR Ensembl; ENSSTOT00000026544.2; ENSSTOP00000015697.2; ENSSTOG00000022370.2.
DR eggNOG; ENOG502SHDP; Eukaryota.
DR GeneTree; ENSGT01090000260043; -.
DR HOGENOM; CLU_012526_0_0_1; -.
DR InParanoid; I3MUA2; -.
DR TreeFam; TF343679; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR CDD; cd15221; 7tmA_OR52B-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26450:SF75; OLFACTORY RECEPTOR 52D1; 1.
DR PANTHER; PTHR26450; OLFACTORY RECEPTOR 56B1-RELATED; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363047};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW Olfaction {ECO:0000256|RuleBase:RU363047};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 28..54
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 60..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 143..166
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 187..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 216..233
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 277..299
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT DOMAIN 44..297
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 319 AA; 35399 MW; 8062BB61EACDB208 CRC64;
MSASNITDKS LPDTLFLTGI PGLEFAHIWI AIPFCVMYLV ALLGNAAIIL VIVMDSALHA
PMYLFLCLLS LTDLALSSTT VPKMLAILWL HAGEISFAGC LAQMFCVHSI YTLESSVLLA
MAFDRYVAIC NPLRYTTILN HIVIGRISIV GVFRSVAIVS PFIFLLRRLL PYCGHHVMAH
TYCEHMGIAW LACANITVNI VYGLTVALLA VGLDSILIFI SYGFILHAVF RLPSQDARRK
ALSTCGSHLG VILIFYIPAF FSFLTHRFGH NRVPKHVHIF LANLYVLVPP VLNPIIYGAR
TKEIRSRLLR LFLLGKIST
//
