ID I3MYW6_ICTTR Unreviewed; 982 AA.
AC I3MYW6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Junction mediating and regulatory protein, p53 cofactor {ECO:0000313|Ensembl:ENSSTOP00000017312.2};
GN Name=JMY {ECO:0000313|Ensembl:ENSSTOP00000017312.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000017312.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000017312.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; AGTP01055343; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01055344; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3MYW6; -.
DR STRING; 43179.ENSSTOP00000017312; -.
DR Ensembl; ENSSTOT00000024495.2; ENSSTOP00000017312.2; ENSSTOG00000021490.2.
DR eggNOG; ENOG502QRHU; Eukaryota.
DR GeneTree; ENSGT00510000046704; -.
DR HOGENOM; CLU_012316_2_0_1; -.
DR InParanoid; I3MYW6; -.
DR TreeFam; TF331023; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0000421; C:autophagosome membrane; IEA:Ensembl.
DR GO; GO:0031252; C:cell leading edge; IEA:Ensembl.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:Ensembl.
DR GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR InterPro; IPR031738; JMY/WHAMM.
DR InterPro; IPR031808; JMY/WHAMM_N.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR23330:SF8; JUNCTION-MEDIATING AND -REGULATORY PROTEIN; 1.
DR PANTHER; PTHR23330; P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED; 1.
DR Pfam; PF15871; JMY; 1.
DR Pfam; PF15920; WHAMM-JMY_N; 2.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 915..932
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 50..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 193..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 961..982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 319..346
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 576..610
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 50..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..749
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..789
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..822
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..881
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..982
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 982 AA; 110771 MW; 46D8AC4B86A18B5B CRC64;
MSFALEETLE SDWVAVRPHV FDEREKHKFV FIVAWNEIEG KFAITCHNRT AQRQRSGSRE
QAGTPVSDGT RGPGSPVGKG RPEATGSATP VRSPGSRRSP TWAEGGSPRS ARCLRGDPPQ
RSPAGRGAES LLRSPARAKP SPVRKGVEAR DAAGSATATQ TAPKEAPVSS VRVVSASGAV
SEEIEVLEMV REDETPLALS DAEQPPPAAE PESPAEECSW AGLFSFQDLR AVHQQLCSVN
SQLEPCLPVF PEEPSGMWTV LFGGAPEMTE QEIDTLCYQL QVYLGHGLDT CGWKILSQVL
FTETDDPEEY YESLSELRQK GYEEVLQRAR KRIQELLDKH KNTESMVELL DLYQMEDEAY
SSLAEATTEL YQYLLQPFRD MRELAMLRRQ QIKISMENDY LGPRRIESLQ KEDADWQRKA
HMAVLSIQDL TVKYFEITAK AQKAVYDRMR ADQKKFGKAS WAAAAERMEK LQYAVSKETL
QMMRAKEICL EQRKHALKEE MQSLQGGTEA IARLDQLEAD YYDLQLQLYE VQFEILKCEE
LLLTAQLESI KRLISEKRDE VVYYDTYESM EAMLEKEEMA ASVHAQREEL QKLQQKARQL
EARRGRVSAK KAYLRNKKEI CIAKHNEKFQ QRIQSEEEYR THHMVQLKRE KVHDEEERKS
AWVSQERQRT LDRLRTFKQR YPGQVILKST RLRLAHARRK SATSPVPHED PCDSLPGVLQ
VEGKTEEVGE GRGQLGSSQT TESQHLSQLE DNSLAQLEAT SLPLSGVTSE LPPTASLPLL
NSSDLEPCSV STDPFPPPLP PTPPPPPPPP PPPPPPPLPV AKDNTANPET LEKGLPRKEG
NEKRIPKSAS APSAHLFDSS QLVSARKKLR KTAEGLQRRR VSSPMDEVLA SLKRGSFHLK
KVEQRTLPPF PDEDDSNNIL AQIRKGVKLK KVQKEVLRES FTLLPDTDPL TRSIHEALRR
IKEASPESED EEEALPCTDW EN
//
