ID I3MZG6_ICTTR Unreviewed; 1108 AA.
AC I3MZG6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Zinc finger CCCH-type containing 4 {ECO:0000313|Ensembl:ENSSTOP00000017512.2};
GN Name=ZC3H4 {ECO:0000313|Ensembl:ENSSTOP00000017512.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000017512.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000017512.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01089518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01089519; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3MZG6; -.
DR Ensembl; ENSSTOT00000021343.2; ENSSTOP00000017512.2; ENSSTOG00000016249.3.
DR GeneTree; ENSGT00940000160011; -.
DR HOGENOM; CLU_008238_0_0_1; -.
DR TreeFam; TF321641; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR045124; Su(sable)-like.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR13119; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI; 1.
DR PANTHER; PTHR13119:SF23; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR Pfam; PF14608; zf-CCCH_2; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00356; ZnF_C3H1; 3.
DR SUPFAM; SSF90229; CCCH zinc finger; 3.
DR PROSITE; PS50103; ZF_C3H1; 3.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 348..375
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 377..404
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 405..428
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 348..375
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 377..404
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 405..428
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..1108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..32
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..87
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..175
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..261
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..300
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..511
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..571
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..740
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 824..846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..952
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1040..1054
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1108 AA; 119701 MW; D85FFBD56AF689DC CRC64;
MPPTFRDTSA AVWEDGELEE GELEDDGAEE TQDTPGGPER SRKEKGEKHH SDSDEEKSHR
RLKRKRKKER EKEKRRSKKR RKSKHKRHAS SSDDFSDFSD DSDFSPSEKG HRKYREYSPP
YAPSHQQYPP SHNTPLPKKA YSKMDSKGYS MYEDYENEQY GEYEGDEEED MGKEDYDDFT
KELNQYRRAK EGSSRGRGSR GRGRGYRGRG SRGGSRGRGM GRGSRGRGRG SVGDHPEDEE
DFYEEEMEYG ESEEPMGDDD YDEYSKELNQ YRRSKDSRGR GLSRGRGRGS RGRGKGMGRG
RGRGGSRGGM NKSGMNDDED FYDDDMGDGG GGSYRRGDHD KPHQQSDKKG KVICKYFVEG
RCTWGDHCNF SHDIELPKKR ELCKFYITGF CARAENCPYM HGDFPCKLYH TTGNCINGDD
CMFSHDPLTE ETRELLDKPG PPQMPMPVHE PLSPQQLQQQ QDMYNKKIPS LFEIVVRPTG
QLAEKLGVRF PGPGGPPGPM GPGPNMGPSG PMGGPMHPDM HPDMHPDMHP DMHPDMHPDM
PMGPGMNPGP PMGPGGPPMM PYGPGDSPHS GMMPPIPPAQ NFYENFYQQQ EGMEMEPGLL
GDTGDTGNWY SSDEDEGGSS VTSILKTLRQ QTSSRPQASV GELSSSGLGD PRLQKGHSSG
GRLADPRLSR DPRLSRHAEA SGGSGTGDSG PSDPRLARSL PTSKPEGSLH SSPAGPSSSK
GPGPTPTEEE EGERALREKA VNIPLDPLPG HPLRDPRSQL QQFSHIKKDV TLSKPSFART
VLWNPEDLIP LPIPKQDVVP PVPAALQSMP ALDPRLHRST PAGPPNARQR SGTSTDPSTS
GSNLPDFELL SRILKTVNAT GPSTAPSPSD KPSDPRVRKA PSDPRLQKTA DSAAPSRAAK
LSPAEAPSPA GSPSGESSPP ATAPYDPRVL AAGGLGQGSG SGQSSVLSGI SLYDPRTPNA
GGKAAEPATD AGAQPKGPEG NGKSATSKAK EPPFVRKSAL EQPETGKAGA DGAAAATDRY
NSYNRPRPKA ASAPATTTVT PPPEGTPPQP GVHNLPVPTL FGTVKPAPKT GSGSPFAGNS
PAREGEQDAG SLKDVFKGFD PTASPFCQ
//
