ID   I3N288_ICTTR            Unreviewed;       134 AA.
AC   I3N288;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Zinc finger protein 593 {ECO:0000313|Ensembl:ENSSTOP00000018484.1};
GN   Name=ZNF593 {ECO:0000313|Ensembl:ENSSTOP00000018484.1};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000018484.1, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Proteomes:UP000005215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000018484.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein
CC       family. {ECO:0000256|ARBA:ARBA00038064}.
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DR   EMBL; AGTP01007760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005317692.1; XM_005317635.1.
DR   AlphaFoldDB; I3N288; -.
DR   STRING; 43179.ENSSTOP00000018484; -.
DR   Ensembl; ENSSTOT00000023260.2; ENSSTOP00000018484.1; ENSSTOG00000022153.2.
DR   GeneID; 101977780; -.
DR   CTD; 51042; -.
DR   eggNOG; KOG3408; Eukaryota.
DR   GeneTree; ENSGT00390000004173; -.
DR   HOGENOM; CLU_117291_1_2_1; -.
DR   InParanoid; I3N288; -.
DR   OMA; MKDHFRS; -.
DR   OrthoDB; 230013at2759; -.
DR   TreeFam; TF315114; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:1990275; F:preribosome binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR   InterPro; IPR022755; Znf_C2H2_jaz.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR46095; ZINC FINGER PROTEIN 593; 1.
DR   PANTHER; PTHR46095:SF1; ZINC FINGER PROTEIN 593; 1.
DR   Pfam; PF12171; zf-C2H2_jaz; 1.
DR   SMART; SM00451; ZnF_U1; 1.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00042}.
FT   DOMAIN          61..90
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          85..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   134 AA;  15060 MW;  C46793F0F8CCBE79 CRC64;
     MGRSRRTGAH RAHSLARQMK AKRRRPDLDE IHRELRPQGP APAKPNRNTE PDPDLPGGGL
     HRCLACGRYF VDSANLKTHF RSKDHKKRLK QLSIEPYSQE EAERAAGMGS YVPPRQLAVP
     TEVSTEVPEM DTSA
//