ID I3N9X4_ICTTR Unreviewed; 1013 AA.
AC I3N9X4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=PHD finger protein 20 {ECO:0000313|Ensembl:ENSSTOP00000021171.2};
GN Name=PHF20 {ECO:0000313|Ensembl:ENSSTOP00000021171.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000021171.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000021171.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01059792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059794; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059797; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059799; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01059801; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005329937.1; XM_005329880.2.
DR AlphaFoldDB; I3N9X4; -.
DR STRING; 43179.ENSSTOP00000021171; -.
DR Ensembl; ENSSTOT00000028989.2; ENSSTOP00000021171.2; ENSSTOG00000024453.2.
DR GeneID; 101968344; -.
DR CTD; 51230; -.
DR eggNOG; KOG1844; Eukaryota.
DR GeneTree; ENSGT00940000156477; -.
DR HOGENOM; CLU_032484_0_0_1; -.
DR InParanoid; I3N9X4; -.
DR OrthoDB; 5491784at2759; -.
DR TreeFam; TF106475; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0071339; C:MLL1 complex; IEA:Ensembl.
DR GO; GO:0044545; C:NSL complex; IEA:Ensembl.
DR GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IEA:Ensembl.
DR CDD; cd20104; MBT_PHF20L1-like; 1.
DR CDD; cd20453; Tudor_PHF20; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041297; Crb2_Tudor.
DR InterPro; IPR043449; PHF20-like.
DR InterPro; IPR022255; PHF20_AT-hook.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR15856:SF27; PHD FINGER PROTEIN 20; 1.
DR PANTHER; PTHR15856; PHD FINGER PROTEIN 20-RELATED; 1.
DR Pfam; PF20826; PHD_5; 1.
DR Pfam; PF12618; PHF20_AT-hook; 1.
DR Pfam; PF18115; Tudor_3; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 455..485
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 142..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..815
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 868..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..520
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..554
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..616
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..809
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..905
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1013 AA; 115507 MW; F0041CA4C9F66892 CRC64;
MTKHPPNRRG ISFEVGAQLE ARDRLKNWYP AHIEDIDYEE GKVLIHFKRW NHRYDEWFCW
DSPYLRPLEK IQLRKEGLHE EDGSSEFQIN EQVLACWSDC RFYPARVTAV NKDGTYTVKF
YDGVVQTVKH IHVKAFSKDQ NIVGNARPKE TDHKSLSSSS DKREKFKEQR KATVNVKKDK
EDKALKSEKR PKLPDKEGKL ICAEKGKVLE KSLPKNEKED KENISENDRE YSADTQVDKK
PENDIVKSPQ ENLREPKRKR GRPPSIAPTA VDSNSQTLQP ITLELRRRKI SKGSDIPLKR
PRLDKNSSQE KSKNCSENAD KDLSRRRSSR LSTNGTHEIL DPNLVVPDLA DKVDTDPSQD
KSSSTKEPEE GQLKSPLEAG SVSSALTCHS FGDGLGAVGL ELNCNSMGEN TMKTEPTSPL
AELQEISTVE VPNTFKKTDD FVTSNAPAVD LDHKFRCKVV DCLKFFRKAK LLHYHMKYFH
GMEKSLEPED SPGKRHVQTR GSSTSDKANQ ESLTRKRVSA SSPTAKDKEK NKEKKFKEFV
RVKPKKKKKK KKKTKPECPC SEEISDTSQE PSPPKAFAVT RCGSSHKPGV HMSPQLHGSE
SGNHKGKLKA VEEENLSESS SESFLWSDEE YGQDVDVTTN PDEELDGDDR YDFEVVRCIC
EVQEENDFMI QCEECQCWQH GVCMGLLEEN VPEKYTCYVC QDPPGQRPGF KYWYDKEWLS
RGHMHGLAFL EENYSHQNAK KIVATHQLLG DVQRVIEVLH GLQLKMSILQ SREHPDLQLW
CQPWKQHSGE GRAQSRHIHG TDARSKEEAS SYRTLNGVVE KPLPLPLPRS VEESYITSEH
CYQKPRAYYP AVEQKLVVET RGSALDDTVN PLCENGDDSL SPRLGWPLDQ DRNRGDNDPK
LSSPKVRDYV SKKVLPEEAP ARKLLDRGGE GLLSSQHQWQ FNLLTHVESL QDEVTHRMDS
IEKELDVLES WLDYTGELEP PEPLARLPQL KHCIKQLLTD LGKVQQIALC CST
//
