ID I3NAM9_ICTTR Unreviewed; 658 AA.
AC I3NAM9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Thrombospondin type 1 domain containing 4 {ECO:0000313|Ensembl:ENSSTOP00000021426.2};
GN Name=THSD4 {ECO:0000313|Ensembl:ENSSTOP00000021426.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000021426.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000021426.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01003475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003479; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003481; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01003484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3NAM9; -.
DR Ensembl; ENSSTOT00000021223.2; ENSSTOP00000021426.2; ENSSTOG00000027069.2.
DR GeneTree; ENSGT00940000156594; -.
DR HOGENOM; CLU_000660_6_1_1; -.
DR TreeFam; TF316874; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR010909; PLAC.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF281; NO LONG NERVE CORD, ISOFORM C; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF08686; PLAC; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 6.
DR SMART; SM00209; TSP1; 6.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS50092; TSP1; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..658
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011482953"
FT DOMAIN 611..648
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT REGION 174..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 73401 MW; 5B8816C4317B85B3 CRC64;
MFVSYLILTL LHVQTAMLAR PGGESIGCDD YLGSDKVVDK CGVCGGDNTG CQVVSGVFKH
ALTSLGYHRV VEIPQGATKI NITEMHKSNN YLALRSRSGR SIINGNWAID RPGKYEGGGT
MFTYKRPNEI SSTAGESFLA EGPTNEILDV YMIHQQPNPG VHYEYVIMGT NAISPQVPPH
RRPGEPLNGQ LDEEGRSQED GEEKEKNGEK EDLPGEASEI FTSESVQTFP VRHPDRFSSH
RPDNLVPPVP QPPRRSRDHN WKQLGTTECS TTCGKGSQYP IFRCVHRNTH EEVPESFCDS
SMKPTPEEEP CNLFPCPAFW DIGEWSECSK TCGLGMQHRQ VLCRQVYANR SLTVQPYRCQ
HLEKPETTST CQLKICSEWQ IRTDWTSCSV PCGVGQRTRD VKCVSNIGDV VDDEECNMKL
RPNDIENCDM GPCAKSWFLT EWSERCSAEC GVGVRTRSVV CMTNHVSSLP LEGCGNNRPA
EATPCDNGPC TGKVEWFAGS WSQCSIGCGS GTQQREVICV RKNADTFEVL DPYECSFLER
PPSQQSCHLQ PCGAKWFSTE WSMCSKSCQG GFRVREVRCL SDDMTLSNLC DPQLKPEERE
SCNPQDCVPE VDENCKDKYY NCNVVVQARL CVYNYYKTAC CASCTRVANR HAGFLGSR
//
