ID I3R5H6_HALMT Unreviewed; 485 AA.
AC I3R5H6; M0J5S7;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 2.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Phosphoesterase {ECO:0000313|EMBL:QCQ75946.1};
DE SubName: Full=TrkA-N domain protein {ECO:0000313|EMBL:AFK19486.2};
GN Name=trkA {ECO:0000313|EMBL:AFK19486.2};
GN OrderedLocusNames=HFX_1782 {ECO:0000313|EMBL:AFK19486.2};
GN ORFNames=C439_01587 {ECO:0000313|EMBL:EMA04326.1}, E6P09_11940
GN {ECO:0000313|EMBL:QCQ75946.1};
OS Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC
OS 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=523841 {ECO:0000313|EMBL:AFK19486.2, ECO:0000313|Proteomes:UP000006469};
RN [1] {ECO:0000313|EMBL:AFK19486.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.2087;
RX PubMed=22247127; DOI=10.1128/AEM.07114-11;
RA Cai S., Cai L., Liu H., Liu X., Han J., Zhou J., Xiang H.;
RT "Identification of the haloarchaeal phasin (PhaP) that functions in
RT polyhydroxyalkanoate accumulation and granule formation in Haloferax
RT mediterranei.";
RL Appl. Environ. Microbiol. 78:1946-1952(2012).
RN [2] {ECO:0000313|EMBL:AFK19486.2, ECO:0000313|Proteomes:UP000006469}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 /
RC R-4 {ECO:0000313|Proteomes:UP000006469}, and CGMCC 1.2087
RC {ECO:0000313|EMBL:AFK19486.2};
RX PubMed=22843593; DOI=10.1128/JB.00880-12;
RA Han J., Zhang F., Hou J., Liu X., Li M., Liu H., Cai L., Zhang B., Chen Y.,
RA Zhou J., Hu S., Xiang H.;
RT "Complete genome sequence of the metabolically versatile halophilic
RT archaeon Haloferax mediterranei, a poly(3-hydroxybutyrate-co-3-
RT hydroxyvalerate) producer.";
RL J. Bacteriol. 194:4463-4464(2012).
RN [3] {ECO:0000313|Proteomes:UP000011603}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 /
RC R-4 {ECO:0000313|Proteomes:UP000011603};
RA Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D., Darling A.,
RA Eisen J.A., Facciotti M.T.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:EMA04326.1, ECO:0000313|Proteomes:UP000011603}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33500 {ECO:0000313|EMBL:EMA04326.1}, and ATCC 33500 / DSM
RC 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4
RC {ECO:0000313|Proteomes:UP000011603};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [5] {ECO:0000313|EMBL:AFK19486.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.2087;
RA Wang L., Yang H., Xiang H.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:QCQ75946.1, ECO:0000313|Proteomes:UP000299011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33500 {ECO:0000313|EMBL:QCQ75946.1}, and ATCC 33500 / DSM
RC 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4
RC {ECO:0000313|Proteomes:UP000299011};
RA DasSarma S., DasSarma P., DasSarma S., Fomenkov A., Vincze T., Anton B.P.,
RA Roberts R.J.;
RT "Methylomes of two halophilic Archaea, Haloarcula marismortui and Haloferax
RT mediterranei.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001868; AFK19486.2; -; Genomic_DNA.
DR EMBL; AOLO01000002; EMA04326.1; -; Genomic_DNA.
DR EMBL; CP039139; QCQ75946.1; -; Genomic_DNA.
DR RefSeq; WP_004056574.1; NZ_CP039139.1.
DR AlphaFoldDB; I3R5H6; -.
DR STRING; 523841.HFX_1782; -.
DR PaxDb; 523841-HFX_1782; -.
DR GeneID; 40157139; -.
DR KEGG; hme:HFX_1782; -.
DR PATRIC; fig|523841.21.peg.320; -.
DR eggNOG; arCOG01566; Archaea.
DR HOGENOM; CLU_046377_1_1_2; -.
DR OrthoDB; 350705at2157; -.
DR Proteomes; UP000006469; Chromosome.
DR Proteomes; UP000011603; Unassembled WGS sequence.
DR Proteomes; UP000299011; Chromosome.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001667; DDH_dom.
DR InterPro; IPR038763; DHH_sf.
DR InterPro; IPR003156; DHHA1_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR47618; BIFUNCTIONAL OLIGORIBONUCLEASE AND PAP PHOSPHATASE NRNA; 1.
DR PANTHER; PTHR47618:SF1; BIFUNCTIONAL OLIGORIBONUCLEASE AND PAP PHOSPHATASE NRNA; 1.
DR Pfam; PF01368; DHH; 1.
DR Pfam; PF02272; DHHA1; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF64182; DHH phosphoesterases; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
FT DOMAIN 12..132
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 485 AA; 52020 MW; F4DDF44807D6C748 CRC64;
MSAGVSVSSM STYAILGCGS VGHAVAEELT DEGKDVLILD KDESRVEALR DQDLNAQATD
IADSELADAV AGRDVILILS SDVEANKAAV STIRGRDDDQ FIVVRASDPV SEDELTELGA
DVVINPSEVI ADSALRSVES GELEYKARQL ADLLRETDHG LAILTHDNPD PDSLASAVAL
QAIAREYDVD ADILYSGDMG HQENRAFVNI LGIELTPRSD AKPLEEYSSV ALVDHMKSGM
PDLGEVDITV FIDHFEPDEG IDARFTDVRP NVSSTSTILT KYIQEFDLSP SQEVATALLY
GIRAETLDFK RDTTPADLTA AAYLYPFADH DTLEKVESPS MSPETLDVLA EAIQNRDVQG
SHLVSNAGFI RDRDALTQAA QHLLNLEGIT TTAVFGIADD TIYLAARSKD IRMNIGKILS
DAFTGIGEAG GHSTQGSVEI PLGIFTGIES SDDNRDTLLQ LTEEAVTRKL FRAMGVEGGE
SGNGS
//
