ID I3TLF6_TISMK Unreviewed; 561 AA.
AC I3TLF6;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Divergent polysaccharide deacetylase family protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=TMO_1755 {ECO:0000313|EMBL:AFK53594.1};
OS Tistrella mobilis (strain KA081020-065).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Geminicoccales;
OC Geminicoccaceae; Tistrella.
OX NCBI_TaxID=1110502 {ECO:0000313|EMBL:AFK53594.1, ECO:0000313|Proteomes:UP000005258};
RN [1] {ECO:0000313|EMBL:AFK53594.1, ECO:0000313|Proteomes:UP000005258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA081020-065 {ECO:0000313|EMBL:AFK53594.1,
RC ECO:0000313|Proteomes:UP000005258};
RX PubMed=22458477; DOI=10.1021/ja301735a;
RA Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H.,
RA Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.;
RT "Bacterial biosynthesis and maturation of the didemnin anti-cancer
RT agents.";
RL J. Am. Chem. Soc. 134:8625-8632(2012).
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DR EMBL; CP003236; AFK53594.1; -; Genomic_DNA.
DR AlphaFoldDB; I3TLF6; -.
DR STRING; 1110502.TMO_1755; -.
DR KEGG; tmo:TMO_1755; -.
DR eggNOG; COG2861; Bacteria.
DR HOGENOM; CLU_485647_0_0_5; -.
DR Proteomes; UP000005258; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd10936; CE4_DAC2; 1.
DR Gene3D; 3.20.20.370; Glycoside hydrolase/deacetylase; 1.
DR InterPro; IPR006837; Divergent_DAC.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR PANTHER; PTHR30105:SF2; DIVERGENT POLYSACCHARIDE DEACETYLASE SUPERFAMILY; 1.
DR PANTHER; PTHR30105; UNCHARACTERIZED YIBQ-RELATED; 1.
DR Pfam; PF04748; Polysacc_deac_2; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005258};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 143..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..254
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 56244 MW; 5E1D7409E7519FC2 CRC64;
MSKGEDGRRD GGAGRKGGGS RKGSDETGTA GRKPAAGSRP RSSATGASKA GASKASASKA
SASKASASKA AGAKAGAAKG ATFRAAGAKP GTAAGKPASK AASRKPASGG TPRSLRGPVG
ASGAEGPGFL ARFGSALLAR RRFLGYGLVG IALLVVAGAV IGSLIKPARY EQVARPTLPA
GAAVTEPARP QAPEAPAAAP EAPRKEWTPD LAGSGDTITG ADASRESQPQ AAATTPPAPA
AKPDPQPAAP KAAPAKPAEA PAAVATAEPA PQQLAAIQPP VPDAIRPPAD GKPAWQRYAM
PAPVASKGPR VAIVIDDMGV NKPQTAAAIG LPSPITFAFL PYAQDVAGQA AKARAAGHEL
IVHMPMQPQG PADPGPGALN PALPVAENVK RLKHNLEAFG AYVGINNHMG SRATEDTPLM
AAVMAELKAR GLLFLDSRTT AKSVGSKAAI SAGIPNVQRD VFLDHEIDER KIAAQLDRLE
AIARRHGAAI AIGHPHPETL KVLNRWLPAA QARGIVFVPL TALVAVPGAS EPAGPRTASD
EAAPARAEEG PVFADGPAVK E
//
