ID I3TTR6_TISMK Unreviewed; 333 AA.
AC I3TTR6;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Pyrimidine biosynthesis enzyme {ECO:0000313|EMBL:AFK56154.1};
GN OrderedLocusNames=TMO_b0146 {ECO:0000313|EMBL:AFK56154.1};
OS Tistrella mobilis (strain KA081020-065).
OG Plasmid pTM2 {ECO:0000313|EMBL:AFK56154.1,
OG ECO:0000313|Proteomes:UP000005258}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Geminicoccales;
OC Geminicoccaceae; Tistrella.
OX NCBI_TaxID=1110502 {ECO:0000313|EMBL:AFK56154.1, ECO:0000313|Proteomes:UP000005258};
RN [1] {ECO:0000313|EMBL:AFK56154.1, ECO:0000313|Proteomes:UP000005258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA081020-065 {ECO:0000313|Proteomes:UP000005258};
RC PLASMID=Plasmid pTM2 {ECO:0000313|Proteomes:UP000005258};
RX PubMed=22458477; DOI=10.1021/ja301735a;
RA Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H.,
RA Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.;
RT "Bacterial biosynthesis and maturation of the didemnin anti-cancer
RT agents.";
RL J. Am. Chem. Soc. 134:8625-8632(2012).
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DR EMBL; CP003238; AFK56154.1; -; Genomic_DNA.
DR AlphaFoldDB; I3TTR6; -.
DR KEGG; tmo:TMO_b0146; -.
DR PATRIC; fig|1110502.3.peg.4402; -.
DR HOGENOM; CLU_028871_1_1_5; -.
DR Proteomes; UP000005258; Plasmid pTM2.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR027939; NMT1/THI5.
DR InterPro; IPR015168; SsuA/THI5.
DR PANTHER; PTHR31528; 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE SYNTHASE THI11-RELATED; 1.
DR PANTHER; PTHR31528:SF15; RIBOFLAVIN-BINDING PROTEIN RIBY; 1.
DR Pfam; PF09084; NMT1; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 4: Predicted;
KW Plasmid {ECO:0000313|EMBL:AFK56154.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005258};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..333
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003679789"
FT DOMAIN 39..245
FT /note="SsuA/THI5-like"
FT /evidence="ECO:0000259|Pfam:PF09084"
SQ SEQUENCE 333 AA; 35764 MW; 1D7BA2B7083C89A7 CRC64;
MKITGTRATV VAAMVAAVWM QPAAAAESVD LVLNWVPTAD HSPYYYAKAQ GWYEEAGIDL
DIQTGKGSGV SAQRVGAGAS KIGIADMATA LLAKSKGADL TAVMVVYANS PQGFYWLKSH
GITGPADFPG HKIGNPPSDA SRVMWPAFAQ KVGIDPASVS FVNVSPQAKM ASLKSGAIDV
TTDFYNEHDL KVREFGDDLG FVAWRDIGIN PYGNAIIVNG DFLKDKPEVV EAFTRVSQRA
FAACVRDVTP CLQALLAAAS GLTEANQRDQ WNRVKELMRD PTTTGTALGA FDPERVAADY
QLVETYFGIE KPFDVTGAYT NDFLDHGIRM TAE
//
