ID I3UB60_ADVKW Unreviewed; 764 AA.
AC I3UB60;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=GTP pyrophosphokinase {ECO:0000313|EMBL:AFK62248.1};
GN OrderedLocusNames=TKWG_09705 {ECO:0000313|EMBL:AFK62248.1};
OS Advenella kashmirensis (strain DSM 17095 / LMG 22695 / WT001)
OS (Tetrathiobacter kashmirensis).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae.
OX NCBI_TaxID=1036672 {ECO:0000313|EMBL:AFK62248.1, ECO:0000313|Proteomes:UP000005267};
RN [1] {ECO:0000313|EMBL:AFK62248.1, ECO:0000313|Proteomes:UP000005267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17095 / LMG 22695 / WT001
RC {ECO:0000313|Proteomes:UP000005267};
RX PubMed=21914874; DOI=10.1128/JB.05781-11;
RA Ghosh W., George A., Agarwal A., Raj P., Alam M., Pyne P., Das Gupta S.K.;
RT "Whole-genome shotgun sequencing of the sulfur-oxidizing chemoautotroph
RT Tetrathiobacter kashmirensis.";
RL J. Bacteriol. 193:5553-5554(2011).
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DR EMBL; CP003555; AFK62248.1; -; Genomic_DNA.
DR AlphaFoldDB; I3UB60; -.
DR STRING; 1036672.TKWG_09705; -.
DR KEGG; aka:TKWG_09705; -.
DR HOGENOM; CLU_012300_3_0_4; -.
DR Proteomes; UP000005267; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd04876; ACT_RelA-SpoT; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR Pfam; PF13291; ACT_4; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS51880; TGS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AFK62248.1};
KW Transferase {ECO:0000313|EMBL:AFK62248.1}.
FT DOMAIN 433..496
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
FT DOMAIN 693..764
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 764 AA; 84516 MW; A3E45FD4058B1E7B CRC64;
MNAVCAGLDD AGRKMVEQAV AWCDPILQDA SIATGEPSIH HAKGMLQILS LLQLDAATLV
AALVLAIPID LEDESAQDQK NELIKLFGLE TFSLINGSRA LLRIGAIARN ASSQGHNESS
GQREMLRKML LAMASDLRIV LIRLASRLQT LRWYAETKNP CPIELAEETR DVYASLANRL
GIWQIKWEME DLSFRFLSPE IYKDIARKLE GKRIEREARI QSLTEDIAGS LADMGIEADV
SGRAKHIYSI YNKMRNKRLT FDQLYDLLAI RIIVANERDC YATLSLLQAR WTPVMNEFDD
YIARPKPNGY RSLHTVLKTA DGHTFEAQIR TRKMHDFAEY GMAAHWRYKE AGPKGGQVAA
VSMYDRQVSW MRQLLAWRKE VGLPVNDPPD SSLQARPETE RAVDAAASVD AGVPAAPEPK
AGQLRQERHN KKTAERIYVL TPQARVIELP EGATPVDFAY HLHTDLGHRC RGARVDGQMV
ALNTKLLNGQ TVEIIAAKSG GPSRDWINTQ LGYLASPRAR AKVRLWFNAI ELQKRITTGQ
DLVEKELARL GKTAINLEQL AERLGFANSD DLYVAVAKDE FSLRQIATAF QEPDPDPGAA
YDTIVARESG AQSAVKTGKS GVLVVGVDSL LTQLARCCHP APPDPIGGFV TRGRGVSIHR
SDCPSFAVMK SKSPERVIEV AWGDTGDTVY PVNIAIHSQD RSGLLKDLTE LFSRMKLNVV
GVNTQSKASI AHLHFTVEVR DGEQLRKAMN AILDIPGIIS AARC
//
