ID   I3UFE6_ADVKW            Unreviewed;       461 AA.
AC   I3UFE6;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:AFK63734.1};
GN   OrderedLocusNames=TKWG_19700 {ECO:0000313|EMBL:AFK63734.1};
OS   Advenella kashmirensis (strain DSM 17095 / LMG 22695 / WT001)
OS   (Tetrathiobacter kashmirensis).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae.
OX   NCBI_TaxID=1036672 {ECO:0000313|EMBL:AFK63734.1, ECO:0000313|Proteomes:UP000005267};
RN   [1] {ECO:0000313|EMBL:AFK63734.1, ECO:0000313|Proteomes:UP000005267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17095 / LMG 22695 / WT001
RC   {ECO:0000313|Proteomes:UP000005267};
RX   PubMed=21914874; DOI=10.1128/JB.05781-11;
RA   Ghosh W., George A., Agarwal A., Raj P., Alam M., Pyne P., Das Gupta S.K.;
RT   "Whole-genome shotgun sequencing of the sulfur-oxidizing chemoautotroph
RT   Tetrathiobacter kashmirensis.";
RL   J. Bacteriol. 193:5553-5554(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP003555; AFK63734.1; -; Genomic_DNA.
DR   RefSeq; WP_014751825.1; NC_017964.1.
DR   AlphaFoldDB; I3UFE6; -.
DR   STRING; 1036672.TKWG_19700; -.
DR   KEGG; aka:TKWG_19700; -.
DR   HOGENOM; CLU_032114_0_0_4; -.
DR   OrthoDB; 9769367at2; -.
DR   Proteomes; UP000005267; Chromosome.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR43796; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR   PANTHER; PTHR43796:SF2; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          5..146
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          150..397
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   461 AA;  50891 MW;  99E00F43FAA5CCDB CRC64;
     MKRNVLIIGA GGVAHVAAHK CAQNNILLGD IHIASRTVAK CEAIIASIKD KGNKHGPGRL
     QAHALDALDI EATKTLIRET GSQIVINVGS PFLNMSVMTA CIETGAAYLD TAIHEDPDKV
     CEPPPWYGNH EWKRREACKK AGVTAVLGVG FDPGVVNAYG RFALDTYFDQ VNSIDIIDIN
     AGSHGRYFAT NFDPEINFRE FTSTVWSWEQ NRWKASKMFE HRQQWEMPVV GNHTTYLTGH
     DELHSMSKNL GVPNIRFWMG FGDHYINVFN VLNSLGLLSE KPIRTAEGDE IVPLKVVKAV
     LPDPASLAPG YTGKTCIGDL VKGTKNGMPQ EVLIYNICDH EESYEEVGSQ AISYTAGVPV
     VAAAMLIADG TWDVGHMVNV EELDPAPFIE LMNRMGLVTR VRDEKGDRVL EPQKELLMLT
     AEEESDSTVA FDYFSHDQAV LAKNPPSRQQ NMMTTRQRLS G
//