ID I3VS78_THESW Unreviewed; 346 AA.
AC I3VS78;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:AFK85373.1};
GN OrderedLocusNames=Tsac_0343 {ECO:0000313|EMBL:AFK85373.1};
OS Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacterium.
OX NCBI_TaxID=1094508 {ECO:0000313|EMBL:AFK85373.1, ECO:0000313|Proteomes:UP000006178};
RN [1] {ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RA Brown S.D., Land M.L., Herring C.D.;
RT "Thermoanaerobacterium saccharolyticum JW/SL-YS485.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFK85373.1, ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RX PubMed=24907337; DOI=10.1128/AEM.00998-14;
RA Currie D.H., Guss A.M., Herring C.D., Giannone R.J., Johnson C.M.,
RA Lankford P.K., Brown S.D., Hettich R.L., Lynd L.R.;
RT "Profile of Secreted Hydrolases, Associated Proteins, and SlpA in
RT Thermoanaerobacterium saccharolyticum during the Degradation of
RT Hemicellulose.";
RL Appl. Environ. Microbiol. 80:5001-5011(2014).
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DR EMBL; CP003184; AFK85373.1; -; Genomic_DNA.
DR RefSeq; WP_014757294.1; NC_017992.1.
DR AlphaFoldDB; I3VS78; -.
DR STRING; 1094508.Tsac_0343; -.
DR KEGG; tsh:Tsac_0343; -.
DR PATRIC; fig|1094508.3.peg.345; -.
DR eggNOG; COG1609; Bacteria.
DR BioCyc; TSAC1094508:GLMA-342-MONOMER; -.
DR Proteomes; UP000006178; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..55
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 346 AA; 38799 MW; 53210A36B3E23F2E CRC64;
MNSKEIAKIA GVSRSTVSRV INNYPNVPPD TREKVLKVIK EYNYVPHASA RMLRGKSSKT
IGLVIVDIKK DSDIHKIYDN VYFGPFTTAV VDFANRIGYN VLITTVFKVK DYKKVKEIFY
NKTISGAIFI GVRNSDPEIK SLIEEGFKIA IVDQEIKEED EIFNKSIIVN MDNLNGAYEA
TKYLINLGHK EIAHISGDLD KLSGFARLEG YKKALKEAGI TYDNHYIVKG SFVEESGYNA
THKLFKKIKP TAIFAANDQM AIGAMQALQE LEYNVPDDVS IIGFDDITIS RYIKPALTTM
SVSLLQMAEL CVENLVKSIE GESEIIAKFL VSAKLIERES CRKISE
//
