ID I3VVL5_THESW Unreviewed; 504 AA.
AC I3VVL5;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Hydrogenase large subunit domain protein {ECO:0000313|EMBL:AFK86560.1};
GN OrderedLocusNames=Tsac_1553 {ECO:0000313|EMBL:AFK86560.1};
OS Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacterium.
OX NCBI_TaxID=1094508 {ECO:0000313|EMBL:AFK86560.1, ECO:0000313|Proteomes:UP000006178};
RN [1] {ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RA Brown S.D., Land M.L., Herring C.D.;
RT "Thermoanaerobacterium saccharolyticum JW/SL-YS485.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFK86560.1, ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RX PubMed=24907337; DOI=10.1128/AEM.00998-14;
RA Currie D.H., Guss A.M., Herring C.D., Giannone R.J., Johnson C.M.,
RA Lankford P.K., Brown S.D., Hettich R.L., Lynd L.R.;
RT "Profile of Secreted Hydrolases, Associated Proteins, and SlpA in
RT Thermoanaerobacterium saccharolyticum during the Degradation of
RT Hemicellulose.";
RL Appl. Environ. Microbiol. 80:5001-5011(2014).
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DR EMBL; CP003184; AFK86560.1; -; Genomic_DNA.
DR RefSeq; WP_014758430.1; NC_017992.1.
DR AlphaFoldDB; I3VVL5; -.
DR STRING; 1094508.Tsac_1553; -.
DR KEGG; tsh:Tsac_1553; -.
DR PATRIC; fig|1094508.3.peg.1574; -.
DR eggNOG; COG2768; Bacteria.
DR eggNOG; COG4624; Bacteria.
DR BioCyc; TSAC1094508:GLMA-1576-MONOMER; -.
DR Proteomes; UP000006178; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd10549; MtMvhB_like; 1.
DR Gene3D; 3.30.70.20; -; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR027631; Mono_FeFe_hydrog.
DR NCBIfam; TIGR04105; FeFe_hydrog_B1; 1.
DR PANTHER; PTHR11615:SF368; HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF00037; Fer4; 2.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 3.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 98..127
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 128..157
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 174..203
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 504 AA; 55601 MW; C46E92AFAE949035 CRC64;
MFKFNTDVQM LKYEVLYNVA KLTLEDRLED EYDEIPYEII PGTKPRFRCC VYKERAIIEQ
RTKVAMGKNL KRTMKHAVDG EEPIIQVLDI ACEECPIKRY RVTEACRGCI THRCTEVCPK
GAITIINKKA NIDYDKCIEC GRCKDACPYN AISDNLRPCI RSCSAKAITM DEELKAAINY
EKCTSCGACT LACPFGAITD KSYIVDIIRA IKSGKKVYAL VAPAIASQFK DVTVGQIKSA
LKEFGFVDVI EVALGADFVA MEEAKEFSHK IKDIKVMTSS CCPAFVAHIK KSYPELSQNI
STTVSPMTAI SKYIKKHDPM AVTVFIGPCT AKKSEVMRDD VKGITDFAMT FEEMVAVLDA
AKIDMKEQQD VEVDDATLFG RKFARSGGVL EAVVEAVKEI GADVEVNPVV CNGLDECNKT
LKIMKAGKLP NNFIEGMACI GGCIGGAGVI NNNVNQAKLA VNKFGDSSYH KSIKDRISQF
DTDDVDFHVD SGEDESSETS FKEA
//
