ID I3WHD9_BIFBI Unreviewed; 332 AA.
AC I3WHD9;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Bifunctional 3-dehydroquinatesynthase/phosphatase {ECO:0000313|EMBL:AFL04302.1};
DE EC=4.2.3.4 {ECO:0000313|EMBL:AFL04302.1};
GN Name=aroB {ECO:0000313|EMBL:AFL04302.1};
GN ORFNames=BBB_0708 {ECO:0000313|EMBL:AFL04302.1};
OS Bifidobacterium bifidum BGN4.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=484020 {ECO:0000313|EMBL:AFL04302.1, ECO:0000313|Proteomes:UP000006173};
RN [1] {ECO:0000313|EMBL:AFL04302.1, ECO:0000313|Proteomes:UP000006173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGN4 {ECO:0000313|EMBL:AFL04302.1,
RC ECO:0000313|Proteomes:UP000006173};
RX PubMed=22887663; DOI=10.1128/JB.00988-12;
RA Yu D.S., Jeong H., Lee D.H., Kwon S.K., Song J.Y., Kim B.K., Park M.S.,
RA Ji G.E., Oh T.K., Kim J.F.;
RT "Complete Genome Sequence of the Probiotic Bacterium Bifidobacterium
RT bifidum Strain BGN4.";
RL J. Bacteriol. 194:4757-4758(2012).
CC -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC {ECO:0000256|ARBA:ARBA00007125}.
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DR EMBL; CP001361; AFL04302.1; -; Genomic_DNA.
DR RefSeq; WP_003817845.1; NC_017999.1.
DR AlphaFoldDB; I3WHD9; -.
DR KEGG; bbf:BBB_0708; -.
DR PATRIC; fig|484020.3.peg.703; -.
DR HOGENOM; CLU_025908_1_2_11; -.
DR Proteomes; UP000006173; Chromosome.
DR GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR003695; Ppx_GppA_N.
DR PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR Pfam; PF02541; Ppx-GppA; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:AFL04302.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006173}.
FT DOMAIN 20..321
FT /note="Ppx/GppA phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02541"
SQ SEQUENCE 332 AA; 35834 MW; 6A504927F87BFC6E CRC64;
MKSVTVAGID CGTNSIRLKI ARVDDQGMHE IVPRILRVIR LGQDVDKTHR FAQDALDRAY
TAAAEFAGVL AQHPVDAIRF VATSATRDAV NRDTFEDGIE QILGVRPEVI PGTEEADLSF
LGATSVVSRG ELEPPYLVVD LGGGSTELVL GGDGIDAPST QVQAAFSMDI GSVRMTERHL
RHDPPSETEI AEAIADIDEH IDEAFRTVPA GRTRTIIGVS GTVTTMSALA LGLKEYDHRR
VDGVRIPVDD AYAVDDRFLR MTREQRRAYK TIHPGRIDVV GGGAVVWNRV LAKVAQAAAA
DHGGVIDSYV ASEHGLLDGI VLDCGRRLLA ER
//
