ID   I3WJ76_BIFBI            Unreviewed;       299 AA.
AC   I3WJ76;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Membrane protease {ECO:0000313|EMBL:AFL04939.1};
GN   Name=hflC {ECO:0000313|EMBL:AFL04939.1};
GN   ORFNames=BBB_1347 {ECO:0000313|EMBL:AFL04939.1};
OS   Bifidobacterium bifidum BGN4.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=484020 {ECO:0000313|EMBL:AFL04939.1, ECO:0000313|Proteomes:UP000006173};
RN   [1] {ECO:0000313|EMBL:AFL04939.1, ECO:0000313|Proteomes:UP000006173}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGN4 {ECO:0000313|EMBL:AFL04939.1,
RC   ECO:0000313|Proteomes:UP000006173};
RX   PubMed=22887663; DOI=10.1128/JB.00988-12;
RA   Yu D.S., Jeong H., Lee D.H., Kwon S.K., Song J.Y., Kim B.K., Park M.S.,
RA   Ji G.E., Oh T.K., Kim J.F.;
RT   "Complete Genome Sequence of the Probiotic Bacterium Bifidobacterium
RT   bifidum Strain BGN4.";
RL   J. Bacteriol. 194:4757-4758(2012).
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DR   EMBL; CP001361; AFL04939.1; -; Genomic_DNA.
DR   AlphaFoldDB; I3WJ76; -.
DR   KEGG; bbf:BBB_1347; -.
DR   PATRIC; fig|484020.3.peg.1332; -.
DR   HOGENOM; CLU_024949_5_0_11; -.
DR   Proteomes; UP000006173; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd03407; SPFH_like_u4; 1.
DR   Gene3D; 3.30.479.30; Band 7 domain; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   PANTHER; PTHR43327:SF31; RESPONSE PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR   PANTHER; PTHR43327; STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:AFL04939.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:AFL04939.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006173};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          21..180
FT                   /note="Band 7"
FT                   /evidence="ECO:0000259|SMART:SM00244"
FT   COILED          172..203
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   299 AA;  33057 MW;  BB28910126124F41 CRC64;
     MTVSLIILGV IVVIVLAVLC ASIFIVPQQQ AYIIERFGKY NKVQFAGIHA KIPFVDRIST
     KTNMRVSQLN VQLETKTLDN VFVTVVASTQ FRVNPENVAT AYYELRDPAG QLRSYMEDAL
     RSAIPALSLD DAFARKDDVA FDVQKTVGAE MARFGFTVVK TLITAIDPSP QVKSAMDSIN
     AAQREKEATR QRAEAQRIQI ETQAAADAEK TRLQGEGQAN YRREIANGIV DQIKSLQAVG
     MDINDVNNVV LFNQYLDVMR SLSESNNTKT VVLPASTPGG YEDLYQQVTK AMLTTNEAK
//