ID I3WK55_BIFBI Unreviewed; 294 AA.
AC I3WK55;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=tRNA guanosine-2'-O-methyl transferase {ECO:0000313|EMBL:AFL05268.1};
DE EC=2.1.1.34 {ECO:0000313|EMBL:AFL05268.1};
GN Name=trm3 {ECO:0000313|EMBL:AFL05268.1};
GN ORFNames=BBB_1678 {ECO:0000313|EMBL:AFL05268.1};
OS Bifidobacterium bifidum BGN4.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=484020 {ECO:0000313|EMBL:AFL05268.1, ECO:0000313|Proteomes:UP000006173};
RN [1] {ECO:0000313|EMBL:AFL05268.1, ECO:0000313|Proteomes:UP000006173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGN4 {ECO:0000313|EMBL:AFL05268.1,
RC ECO:0000313|Proteomes:UP000006173};
RX PubMed=22887663; DOI=10.1128/JB.00988-12;
RA Yu D.S., Jeong H., Lee D.H., Kwon S.K., Song J.Y., Kim B.K., Park M.S.,
RA Ji G.E., Oh T.K., Kim J.F.;
RT "Complete Genome Sequence of the Probiotic Bacterium Bifidobacterium
RT bifidum Strain BGN4.";
RL J. Bacteriol. 194:4757-4758(2012).
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DR EMBL; CP001361; AFL05268.1; -; Genomic_DNA.
DR RefSeq; WP_014760691.1; NC_017999.1.
DR AlphaFoldDB; I3WK55; -.
DR KEGG; bbf:BBB_1678; -.
DR PATRIC; fig|484020.3.peg.1661; -.
DR HOGENOM; CLU_085947_0_0_11; -.
DR Proteomes; UP000006173; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0141100; F:tRNA (guanine(18)-2'-O)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 2.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AFL05268.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006173};
KW Transferase {ECO:0000313|EMBL:AFL05268.1}.
FT DOMAIN 205..287
FT /note="tRNA/rRNA methyltransferase SpoU type"
FT /evidence="ECO:0000259|Pfam:PF00588"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 294 AA; 32351 MW; 60132268D0551741 CRC64;
MHKPNPISLA AKASGEPEFR EVGVGPWTQE HPGEPRPDDL KSPNYDRRYD TTLLDEGDRR
NVLDRYRYWT VNAIRDDLDA AGRHGFDVAI ENWTHDFNIG SMVRTANAFT ANRVHIVGPH
KWNRKGSLMT ELYQHVEYHP SIDELVTCWK LRIAGEIAAA QAQAAAAAMH AHQAHSDASA
LLSDDDKSNG SPRFASATDH SGYDAVARAD ARIRTLESSR IIALDIIPGA VPMETYRFPE
RCLMLFGAEG PGLSNKALEL ADDVVYISQF GSVRSINAGA AAAVAMHSWI AQHG
//
