ID I3ZDT1_TERRK Unreviewed; 444 AA.
AC I3ZDT1;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=inositol-3-phosphate synthase {ECO:0000256|ARBA:ARBA00012125};
DE EC=5.5.1.4 {ECO:0000256|ARBA:ARBA00012125};
GN OrderedLocusNames=Terro_1078 {ECO:0000313|EMBL:AFL87399.1};
OS Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63).
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Terriglobus.
OX NCBI_TaxID=926566 {ECO:0000313|EMBL:AFL87399.1, ECO:0000313|Proteomes:UP000006056};
RN [1] {ECO:0000313|EMBL:AFL87399.1, ECO:0000313|Proteomes:UP000006056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18391 / NRRL B-41598 / KBS 63
RC {ECO:0000313|Proteomes:UP000006056};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Munk A.C.C.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "Complete genome of Terriglobus roseus DSM 18391.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- PATHWAY: Polyol metabolism; myo-inositol biosynthesis; myo-inositol
CC from D-glucose 6-phosphate: step 1/2. {ECO:0000256|ARBA:ARBA00005117}.
CC -!- SIMILARITY: Belongs to the myo-inositol 1-phosphate synthase family.
CC {ECO:0000256|ARBA:ARBA00010813}.
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DR EMBL; CP003379; AFL87399.1; -; Genomic_DNA.
DR RefSeq; WP_014784968.1; NC_018014.1.
DR AlphaFoldDB; I3ZDT1; -.
DR STRING; 926566.Terro_1078; -.
DR KEGG; trs:Terro_1078; -.
DR PATRIC; fig|926566.3.peg.1062; -.
DR eggNOG; COG1260; Bacteria.
DR HOGENOM; CLU_021486_0_0_0; -.
DR OrthoDB; 729130at2; -.
DR Proteomes; UP000006056; Chromosome.
DR GO; GO:0004512; F:inositol-3-phosphate synthase activity; IEA:InterPro.
DR GO; GO:0006021; P:inositol biosynthetic process; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002587; Myo-inos-1-P_Synthase.
DR InterPro; IPR013021; Myo-inos-1-P_Synthase_GAPDH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR11510:SF5; INOSITOL-3-PHOSPHATE SYNTHASE 1; 1.
DR PANTHER; PTHR11510; MYO-INOSITOL-1 PHOSPHATE SYNTHASE; 1.
DR Pfam; PF01658; Inos-1-P_synth; 1.
DR Pfam; PF07994; NAD_binding_5; 1.
DR PIRSF; PIRSF015578; Myoinos-ppht_syn; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000006056}.
FT DOMAIN 251..363
FT /note="Myo-inositol-1-phosphate synthase GAPDH-like"
FT /evidence="ECO:0000259|Pfam:PF01658"
SQ SEQUENCE 444 AA; 49457 MW; C24EF4878E4F1D1E CRC64;
MTESPTPQAA AIAPAQGKLG IMIPGMGAVA TTLIAGVEAV RRGMAKPIGS MTQMGTIRLG
KRTDDNTPLI KDFAPIAQLE DLVFTGWDIF GGNLYDAAKT AHVLDRDQLE EMRPFLEGIE
PMPAAFDQRY IKRLEPKKIK TGKNKCDLAN QIRNDIAEFK AKTDRQVMIW TGSTEIYITE
SAVHQSLAAF EKGLVEDDEN IAPSMLYAWA CLKEGVPFIN GAPNLSCDIP ALRELSKTMG
APIAGKDFKT GQTFIKTVLA PALKVRQLGL AGWYSTNILG NRDGEVLDDP DNFKTKEESK
LGVLEYILQP DKNPDLYKDF YHKVRINYYP PRGDNKEGWD NIDLFGWLGY PMQLKVDFLC
RDSILAAPLA LDLCLYMDLA ARTPALKNLG IQEWLSFYFK APDTAPGVYP EHDLFIQNMK
LKNTLRHIMG ESLVTHLGLD YYGE
//
