ID I4B6D8_TURPD Unreviewed; 778 AA.
AC I4B6D8;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN OrderedLocusNames=Turpa_2200 {ECO:0000313|EMBL:AFM12845.1};
OS Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H)
OS (Leptospira parva).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Turneriella.
OX NCBI_TaxID=869212 {ECO:0000313|EMBL:AFM12845.1, ECO:0000313|Proteomes:UP000006048};
RN [1] {ECO:0000313|EMBL:AFM12845.1, ECO:0000313|Proteomes:UP000006048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H
RC {ECO:0000313|Proteomes:UP000006048};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Chertkov O.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete chromosome of genome of Turneriella parva DSM 21527.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family.
CC {ECO:0000256|ARBA:ARBA00009580}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002959; AFM12845.1; -; Genomic_DNA.
DR RefSeq; WP_014803351.1; NC_018020.1.
DR AlphaFoldDB; I4B6D8; -.
DR STRING; 869212.Turpa_2200; -.
DR KEGG; tpx:Turpa_2200; -.
DR PATRIC; fig|869212.3.peg.2213; -.
DR HOGENOM; CLU_362391_0_0_12; -.
DR OrthoDB; 9806482at2; -.
DR Proteomes; UP000006048; Chromosome.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14505; CDKN3-like; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR022778; CDKN3.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR045544; TCAD9.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR23339:SF98; CYCLIN-DEPENDENT KINASE INHIBITOR 3-RELATED; 1.
DR PANTHER; PTHR23339; TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE; 1.
DR Pfam; PF05706; CDKN3; 1.
DR Pfam; PF19974; TCAD9; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000006048}.
FT DOMAIN 630..778
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 700..754
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 706..760
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 778 AA; 87559 MW; DE1FDCB009939C85 CRC64;
MASILITQCL QNDFVRLLDK YDPLPNYLHI GYDEAMRLLG ERAEEGPVAQ IIRWAYEQSE
DALKIIHIRD WHSADDSEQQ SHLEQFGRHC LANSEGADFV FTRQLPAAHA RRPDIVVNAS
GLNDFYKTDL AEHLTEAGQG ESLRIGLIGV WTEAKITYLA YELVTRYPKI ELVTCSALTA
SSARSQHFIA LDHLKRILGV KVFDSVASFA EYLGGTGHGL TASAYAENRQ LDAAKFTFNI
PYDLKEADAK ILHYLFRDSK SADFICLDGG FSGNVVLKAE SRDIYGQKQQ PTVVKIGQRD
PISRERASFE RIQEVLGNSA PAVVDFAEFG ERGGIKYRYA AMTDGKVKNF QKVFAESSDL
EQLKKYLHIV FRRQLGRFYE AAVQENLNLL DYYDFKPKYA DSVRRKCAEL AEFTSDRKLK
LADGIEVEDV SKFYAEDLLH LRETVAMPRY VSWLHGDLNG ANIIIDESQN VWLIDFFHTH
RGHALKDLIK LENDILYIFT KINSADDLRL ACRATDWLFE VHDLAVAPDE PPAELAADAR
FAKSLAIIGY LRSLYRDIID LDRDPYQFFV AAARYAMHTL SFDECNLWQR KWALYAGAMA
IGRVRDALTK SARLRIDFMT TTGEASPEGS IGLTILPGRK DRGRDLAEDI AAIKSAGVTA
VVTLLSHAEF AEYGVANLLD AYRDAGLEVL HRAVKDQGVP TAEQAEQALQ FLKQTTDADK
KVLIHCVGGL GRTGLIAALF LRRYAGLDGD EAMRRVRAAR SPRAIENTDQ ENYVKNWK
//
