ID I4BC35_MYCCN Unreviewed; 144 AA.
AC I4BC35;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Cell wall synthesis protein CwsA {ECO:0000256|HAMAP-Rule:MF_00927};
DE AltName: Full=Cell wall synthesis and cell shape protein A {ECO:0000256|HAMAP-Rule:MF_00927};
GN Name=cwsA {ECO:0000256|HAMAP-Rule:MF_00927};
GN OrderedLocusNames=Mycch_0013 {ECO:0000313|EMBL:AFM14842.1};
OS Mycolicibacterium chubuense (strain NBB4) (Mycobacterium chubuense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710421 {ECO:0000313|EMBL:AFM14842.1, ECO:0000313|Proteomes:UP000006057};
RN [1] {ECO:0000313|EMBL:AFM14842.1, ECO:0000313|Proteomes:UP000006057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB4 {ECO:0000313|EMBL:AFM14842.1,
RC ECO:0000313|Proteomes:UP000006057};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T.,
RA Holmes A., Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of chromosome of Mycobacterium chubuense NBB4.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for regulated cell division, cell wall synthesis and
CC the maintenance of cell shape. {ECO:0000256|HAMAP-Rule:MF_00927}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00927};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00927}.
CC Note=Localizes to poles and midcell sites. {ECO:0000256|HAMAP-
CC Rule:MF_00927}.
CC -!- SIMILARITY: Belongs to the CwsA family. {ECO:0000256|HAMAP-
CC Rule:MF_00927}.
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DR EMBL; CP003053; AFM14842.1; -; Genomic_DNA.
DR RefSeq; WP_014813334.1; NC_018027.1.
DR AlphaFoldDB; I4BC35; -.
DR STRING; 710421.Mycch_0013; -.
DR KEGG; mcb:Mycch_0013; -.
DR PATRIC; fig|710421.3.peg.11; -.
DR eggNOG; ENOG5030K8D; Bacteria.
DR HOGENOM; CLU_1914740_0_0_11; -.
DR OrthoDB; 4762208at2; -.
DR Proteomes; UP000006057; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0042546; P:cell wall biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00927; CwsA; 1.
DR InterPro; IPR024245; CwsA.
DR Pfam; PF10814; CwsA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00927};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00927};
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00927};
KW Cell shape {ECO:0000256|HAMAP-Rule:MF_00927};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_00927};
KW Reference proteome {ECO:0000313|Proteomes:UP000006057};
KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_00927};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00927}.
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00927"
SQ SEQUENCE 144 AA; 15166 MW; 1A12829B0BFF9947 CRC64;
MRSTTTVRLS PSQRLSRGLK YTAVGPVDVT RGAVGLGVGS LMSSASWVGD RYRNGQLSRR
LKADLAAAQE SIAAEIAAAQ DVVANLPEAL EKARKSRRRR RPLLIAGVGV VVLAGGAAAF
SIIRRSTQPE PSPLPPSVEV TPKP
//
