ID I4BH60_MYCCN Unreviewed; 533 AA.
AC I4BH60;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II {ECO:0000313|EMBL:AFM16617.1};
GN OrderedLocusNames=Mycch_1827 {ECO:0000313|EMBL:AFM16617.1};
OS Mycolicibacterium chubuense (strain NBB4) (Mycobacterium chubuense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710421 {ECO:0000313|EMBL:AFM16617.1, ECO:0000313|Proteomes:UP000006057};
RN [1] {ECO:0000313|EMBL:AFM16617.1, ECO:0000313|Proteomes:UP000006057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB4 {ECO:0000313|EMBL:AFM16617.1,
RC ECO:0000313|Proteomes:UP000006057};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T.,
RA Holmes A., Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of chromosome of Mycobacterium chubuense NBB4.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003053; AFM16617.1; -; Genomic_DNA.
DR RefSeq; WP_014815098.1; NC_018027.1.
DR AlphaFoldDB; I4BH60; -.
DR STRING; 710421.Mycch_1827; -.
DR KEGG; mcb:Mycch_1827; -.
DR PATRIC; fig|710421.3.peg.1831; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_2_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000006057; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05904; 4CL; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AFM16617.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006057}.
FT DOMAIN 31..400
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 451..526
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 533 AA; 55719 MW; D454FF78471CE9B5 CRC64;
MSFPSPFPEV DIPTASVYEY LFSGLGDADL DRVALTDAKS GRATTYRELV ARIDTFAGAL
AARGVGVGDV IGLLAPNSSA FAVAFHGILR AGATATTINA LFRAKDIAKQ LTDAKATMLV
TVAALLPQAE EGAAAAGIPA DNLVVLDGAG RDTDGHPNAA DLLAAGAAAP AVTFAPSSHL
AALPYSSGTT GNPKGVMLTH RNLVANVAQI RPLHGMVADD VVLAVLPFFH IYGMTVLLNA
ALHARARLVI MPSFDLGEFL GNIAEHKCTI AFIAPPVAVA LAKHPLVDEH DLSSLKVVMS
GAAPLDADLG HAVAQRLDCR VVQGYGMSEL SPVSHITPFD SGRLDMHVDA PLSSVGWTVS
NAVSKIVDPE TGAEIGVPAE GLSETGELLF KGPNVMAGYL NNDEATRATI DDDGWLHTGD
LARVDAHGCV YIVDRLKELI KYKGYQVPPA ELEAVLLSHP EIVDAAVVGV LDGEGEEVPK
AFVVTQGDSA LTDADVMEFV AGQVAPYKKV RQVEFIDAIP KSSSGKILRK DLK
//
