ID I4BR72_MYCCN Unreviewed; 804 AA.
AC I4BR72;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Trehalose/maltose hydrolase or phosphorylase {ECO:0000313|EMBL:AFM19779.1};
GN OrderedLocusNames=Mycch_5093 {ECO:0000313|EMBL:AFM19779.1};
OS Mycolicibacterium chubuense (strain NBB4) (Mycobacterium chubuense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710421 {ECO:0000313|EMBL:AFM19779.1, ECO:0000313|Proteomes:UP000006057};
RN [1] {ECO:0000313|EMBL:AFM19779.1, ECO:0000313|Proteomes:UP000006057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB4 {ECO:0000313|EMBL:AFM19779.1,
RC ECO:0000313|Proteomes:UP000006057};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T.,
RA Holmes A., Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of chromosome of Mycobacterium chubuense NBB4.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC {ECO:0000256|ARBA:ARBA00006768}.
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DR EMBL; CP003053; AFM19779.1; -; Genomic_DNA.
DR AlphaFoldDB; I4BR72; -.
DR STRING; 710421.Mycch_5093; -.
DR KEGG; mcb:Mycch_5093; -.
DR PATRIC; fig|710421.3.peg.5076; -.
DR eggNOG; COG1554; Bacteria.
DR HOGENOM; CLU_006285_2_2_11; -.
DR OrthoDB; 9816160at2; -.
DR Proteomes; UP000006057; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR005194; Glyco_hydro_65_C.
DR InterPro; IPR005195; Glyco_hydro_65_M.
DR InterPro; IPR005196; Glyco_hydro_65_N.
DR InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11051:SF13; GLYCOSYL TRANSFERASE-RELATED; 1.
DR Pfam; PF03633; Glyco_hydro_65C; 1.
DR Pfam; PF03632; Glyco_hydro_65m; 1.
DR Pfam; PF03636; Glyco_hydro_65N; 1.
DR PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000313|EMBL:AFM19779.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006057}.
FT DOMAIN 17..271
FT /note="Glycoside hydrolase family 65 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03636"
FT DOMAIN 328..679
FT /note="Glycoside hydrolase family 65 central catalytic"
FT /evidence="ECO:0000259|Pfam:PF03632"
FT DOMAIN 688..750
FT /note="Glycoside hydrolase family 65 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03633"
FT REGION 748..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..777
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 489
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT BINDING 362..363
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT BINDING 591..592
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ SEQUENCE 804 AA; 88477 MW; 6EF04583EA954340 CRC64;
MMIVDDAFPV EPWLVRETEL CLDLLPQTES LFALSNGHIG LRGNLDEGEP YGLPGTYLNG
FYEIRPLPYA EAGFGYPEDG QSIVDVTNGK LIRLLVEDEP FDVRYGDLLS HERILDMRAG
TLTRTAEWCS PAGKRVKVTS VRLVSLAQRG LAAIEYVVEA VGDDVRVTLQ SELVANEDQP
ATSGDPRVAA VLVNPLEPIQ HEVSDRGALL IHRTRSSGLM LAAAMDHAVD APGRVDFDGD
AGADWARTTV VCGLKSGERL RIVKYLAYGW SSLRSRPALR DQAAAAIAAA RYTGWQGLLD
EQRAYLDAFW DCADVEVDGD ADCQQAVRFG LFHVMQASAR AERRAIAGKG LTGTGYDGHT
FWDSEGYVLP VLTYTAPHAA ADALRWRAST LDLARSRARE LDLAGASFPW RTIAGEECSA
YWPAGTAAFH VNADIAMAFE RYRVVTGDDS LEKSCGLAVL VDTARLWLSL GHHDRHGAWR
IDGVTGPDEY TAVVRDNVFT NLMAAANLRT AADACTRHPD LACELGVGTE ETAAWRDAAD
AVHIPYDHEL GVHPQCEGFT TLREWDFTAN TEYPLLLHEP YVRLYPAQVI KQADLVLAMH
WQSHAFTAEQ KARNVDYYER RTTRDSSLSA CTQAVMCAEV GHLELAHDYA YEAALIDLRN
LHHNTGDGLH LASLAGSWTA LVAGFGGLRD DEGVLALDPH LPSGISRLRF RLRWRDFRVT
VEATHTSVTY TLRDGPHTTL TIRHAGEPLE ITTDSPTRAP VRPRTPLLPP PPQPAGREPL
RRHVQGHTSS REPMITVRSS GRPK
//
