ID I4CCX6_DESTA Unreviewed; 1164 AA.
AC I4CCX6;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Desti_4800 {ECO:0000313|EMBL:AFM27417.1};
OS Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1).
OC Bacteria; Thermodesulfobacteriota; Desulfomonilia; Desulfomonilales;
OC Desulfomonilaceae; Desulfomonile.
OX NCBI_TaxID=706587 {ECO:0000313|EMBL:AFM27417.1, ECO:0000313|Proteomes:UP000006055};
RN [1] {ECO:0000313|Proteomes:UP000006055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49306 / DSM 6799 / DCB-1
RC {ECO:0000313|Proteomes:UP000006055};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Zeytun A.,
RA Lu M., Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "Complete sequence of chromosome of Desulfomonile tiedjei DSM 6799.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003360; AFM27417.1; -; Genomic_DNA.
DR RefSeq; WP_014812524.1; NC_018025.1.
DR AlphaFoldDB; I4CCX6; -.
DR STRING; 706587.Desti_4800; -.
DR KEGG; dti:Desti_4800; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2204; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_000445_114_51_7; -.
DR OrthoDB; 9813024at2; -.
DR Proteomes; UP000006055; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 5.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 4.
DR SMART; SM00091; PAS; 6.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 5.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 4.
DR PROSITE; PS50112; PAS; 4.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000006055}.
FT DOMAIN 153..223
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 227..278
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 279..349
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 354..405
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 406..478
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 481..533
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 534..576
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 731..787
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 800..1023
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1043..1159
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 122..156
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1094
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1164 AA; 131933 MW; 0F168358D02D144C CRC64;
MPFEGDLGTA LQDEEPFTFR EWARILPVPT ILLNANFTVN TVNPACKSLG SQLAKLRGLP
FSNLFPDPSE SSLVQNMLEH IISDGKIRTC KAHLRIADRE MRVDLTGRRF SQKKRNFVLL
VIDSLASEKE HARKVVKKAI EEREKAERAL AESQTRFEQF VAHVSDIIVT TDIKGCFTFV
NPPGLKLIGC TAEELLGTRF FDLVHPAYRK RAEKFYSTQF AKRKATTYYE VPVIDRSGKI
MWLGQNVQLL FETDRIIGFK AISRNITDRR LAEDELKKSQ RRYKDLFENA NDVIYTHDLK
GNYLSVNDAI TRILGYEREE FLKSRYQDFI APSSLPLVRE NLRLKVEQGI QCTGPYEILV
RSKSGKPVWM EITSRLMLKE GKPIGIHGIA RDVTDRRLVQ DRLNESQELY SIVTEQTGQL
IYEYDPATGK VKWSGAIEAT TGYTIQELVS DTRGWRKLIH PEDRFEAVAA FERAVARGVS
FQIDYRFKRK DGTYIWIEDK GLCQKDESGS VFRVLGIMKD ISGRKHVETA LDLERKKFQI
LVDNAPFALM MLSQSNDLAY VNPKFKELFG YDLQEVPNGR EWLRKAFPES AYRKQVIASW
MQDMRKGATG EQRPRTFKVR CKDGTDKLIH FIPVQLSTGD QIVSCEDITY RIQGEKALQE
RERFLASVFS CIQDGLSIMD KDLRIIRTNA TMQKWYKHDE PLIGKKCHEA YQGIDEVCPS
CPALQTLKTG QATSFVIPKG GPANSITGWL DVCTFPLVVE SSGEIEGVIV HLRDVTERRH
LEEQLRQASK MEAIGTLAGG LAHDFNNLLQ IVLGYADLLL LGKNKAESDY QRILAIRTAA
KRGSDVVQRI LTFSRKVETK LRPVNLNQEL RFMEDLLRST MPKNIAVKLQ LAENPVMIQA
DPTQIEQIVL NLAVNAKQAM PKGGNFVLET RTVDLDRDYC RTRPETKPGK YVMLMVSDTG
KGMDKDVLDR VFEPFFTTKQ PGEGTGLGLS IVFGIVKSHL GHITCSSEPE VGTVFKLYFP
LLKEQFESFA ETTQQMPAFG SETLLMIDDE ESIRNLGKEL LNEAGYNVLT AGSGQEALRI
YREIWEGVSL VILDLVMPDM SGLECLEELL KVNPDVKVLI ASGYSPANQG REILELGAVG
FVSKPYNFKQ ILAAVRAALD YRHK
//
