ID I4CEF8_DESTA Unreviewed; 338 AA.
AC I4CEF8;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Methanol-specific methylcobalamin: coenzyme M methyltransferase {ECO:0000313|EMBL:AFM27949.1};
GN OrderedLocusNames=Desti_5361 {ECO:0000313|EMBL:AFM27949.1};
OS Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1).
OC Bacteria; Thermodesulfobacteriota; Desulfomonilia; Desulfomonilales;
OC Desulfomonilaceae; Desulfomonile.
OX NCBI_TaxID=706587 {ECO:0000313|EMBL:AFM27949.1, ECO:0000313|Proteomes:UP000006055};
RN [1] {ECO:0000313|Proteomes:UP000006055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49306 / DSM 6799 / DCB-1
RC {ECO:0000313|Proteomes:UP000006055};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Zeytun A.,
RA Lu M., Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "Complete sequence of chromosome of Desulfomonile tiedjei DSM 6799.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP003360; AFM27949.1; -; Genomic_DNA.
DR RefSeq; WP_014813048.1; NC_018025.1.
DR AlphaFoldDB; I4CEF8; -.
DR STRING; 706587.Desti_5361; -.
DR KEGG; dti:Desti_5361; -.
DR eggNOG; COG0407; Bacteria.
DR HOGENOM; CLU_040933_2_1_7; -.
DR OrthoDB; 8452307at2; -.
DR Proteomes; UP000006055; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR006360; Mtase_MtaA_CmuA.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR NCBIfam; TIGR01463; mtaA_cmuA; 1.
DR PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR Pfam; PF01208; URO-D; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
KW Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW Methyltransferase {ECO:0000313|EMBL:AFM27949.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006055};
KW Transferase {ECO:0000313|EMBL:AFM27949.1}.
FT DOMAIN 3..334
FT /note="Uroporphyrinogen decarboxylase (URO-D)"
FT /evidence="ECO:0000259|Pfam:PF01208"
SQ SEQUENCE 338 AA; 36996 MW; DC5B24701EB00ED6 CRC64;
MTLKEKFMNR LSGSGSDETL YGCTTTYGVV DLMEKCGYQR PLADTDPVAM TELALAGYRY
AGFEWIKAMG WDITAISEAL GCTLGPTEID RQYSIKEHPF AESLEGLDYP SDFLQRGRFP
VYKQHFQMLK DKIGDEVAIF GETEGPFTAA ANLVGAEEFM KWTIKRPADV QKVLEVTTQA
AIDAINFAFD NGADYYVLAE PTSGPAVMSG RSWAKFMLPL MKEVVSKSKG PLVLHICGNT
DSIIGLMCDS GVAGISIEEK ADMKKAKEIA GPKGVKVFGN VATATTLFMG KPEECYQEAI
AALENGTDFL TPGCGIAPRS PLENLLQMKK ARDNFHRK
//
