ID I4DAS4_DESAJ Unreviewed; 451 AA.
AC I4DAS4;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE {ECO:0000256|ARBA:ARBA00013280};
GN OrderedLocusNames=Desaci_4033 {ECO:0000313|EMBL:AFM42898.1};
OS Desulfosporosinus acidiphilus (strain DSM 22704 / JCM 16185 / SJ4).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=646529 {ECO:0000313|EMBL:AFM42898.1, ECO:0000313|Proteomes:UP000002892};
RN [1] {ECO:0000313|EMBL:AFM42898.1, ECO:0000313|Proteomes:UP000002892}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22704 / JCM 16185 / SJ4
RC {ECO:0000313|Proteomes:UP000002892};
RX PubMed=23105050; DOI=10.1128/JB.01392-12;
RA Pester M., Brambilla E., Alazard D., Rattei T., Weinmaier T., Han J.,
RA Lucas S., Lapidus A., Cheng J.F., Goodwin L., Pitluck S., Peters L.,
RA Ovchinnikova G., Teshima H., Detter J.C., Han C.S., Tapia R., Land M.L.,
RA Hauser L., Kyrpides N.C., Ivanova N.N., Pagani I., Huntmann M., Wei C.L.,
RA Davenport K.W., Daligault H., Chain P.S., Chen A., Mavromatis K.,
RA Markowitz V., Szeto E., Mikhailova N., Pati A., Wagner M., Woyke T.,
RA Ollivier B., Klenk H.P., Spring S., Loy A.;
RT "Complete genome sequences of Desulfosporosinus orientis DSM765T,
RT Desulfosporosinus youngiae DSM17734T, Desulfosporosinus meridiei DSM13257T,
RT and Desulfosporosinus acidiphilus DSM22704T.";
RL J. Bacteriol. 194:6300-6301(2012).
CC -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC prosthetic group of nitrogenase (FeMo cofactor).
CC {ECO:0000256|ARBA:ARBA00003171}.
CC -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005155}.
CC -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family.
CC {ECO:0000256|ARBA:ARBA00011002, ECO:0000256|RuleBase:RU004021}.
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DR EMBL; CP003639; AFM42898.1; -; Genomic_DNA.
DR RefSeq; WP_014828884.1; NC_018068.1.
DR AlphaFoldDB; I4DAS4; -.
DR STRING; 646529.Desaci_4033; -.
DR KEGG; dai:Desaci_4033; -.
DR eggNOG; COG2710; Bacteria.
DR HOGENOM; CLU_025876_1_1_9; -.
DR OrthoDB; 9767044at2; -.
DR UniPathway; UPA00782; -.
DR Proteomes; UP000002892; Chromosome.
DR GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR Gene3D; 3.40.50.12380; Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal; 1.
DR Gene3D; 3.40.50.1980; Nitrogenase molybdenum iron protein domain; 1.
DR InterPro; IPR000510; Nase/OxRdtase_comp1.
DR InterPro; IPR000318; Nase_comp1_CS.
DR InterPro; IPR005973; NifE.
DR NCBIfam; TIGR01283; nifE; 1.
DR PANTHER; PTHR42956; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR PANTHER; PTHR42956:SF1; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR Pfam; PF00148; Oxidored_nitro; 1.
DR SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR PROSITE; PS00699; NITROGENASE_1_1; 1.
PE 3: Inferred from homology;
KW Nitrogen fixation {ECO:0000256|ARBA:ARBA00023231,
KW ECO:0000256|RuleBase:RU004021}.
FT DOMAIN 38..434
FT /note="Nitrogenase/oxidoreductase component 1"
FT /evidence="ECO:0000259|Pfam:PF00148"
SQ SEQUENCE 451 AA; 48938 MW; 3553E278E9FE6C72 CRC64;
MFTNLSKLDL KDKPSLAEAG SPKLCMKALP GEGAERSCAY DGARVVLMPI TDVAHLVHGP
IACAGNSWDN RGARSSGSQL YRRGLTTDLL ENDVIYGGEQ KLKEAILEIA AKHQPKAIFV
YATCVSALIG DDMSKICAEA EAELPIPIIP VNAPGFLGDK NIGNRIAGEV LFERVIGTGG
GPPEKIPLSI NLIGEYNIAG DLWGILPDLK NLGITLQTAI TGDAKFDDIR SAHRACLNVL
ICSKSLTNLA RKMEIRYGIP FIEGSFYGIH DTSETLINIA KALNDPELLT RTQAYVQKRE
VETREIIAQH KKKLENKQAI LFTGGVKTWS MVSTLAELGI NILAGGTQNS TPEDFQRMKE
LMDPSAQIIE DTSSAGFLKI IAEKKPDLIV AGGKTKYLAH KTRTPFLDIN HGRKLPYAGY
QGMVTFAESL TRTVFSPVWG HLKAKFPPVG G
//
